Treatment Overview
The Nucleofill Revitalizing Injection is one of Korea’s most advanced anti-aging skin booster treatments, formulated with polynucleotides (PN) that deeply repair, hydrate, and stimulate the skin’s natural regeneration process. Unlike fillers that simply add volume, Nucleofill works biologically to enhance elasticity, improve circulation, and restore skin density, making it highly effective for tired, sagging, or dull skin.
Korean dermatology clinics have perfected revitalization protocols using Nucleofill, offering natural and long-lasting results with minimal downtime. Patients choose this treatment to achieve firmer, brighter, and healthier skin through the most advanced K-beauty techniques.
Purpose & Benefits
- Skin Revitalization: Restores dermal vitality and improves tone.
- Collagen & Elastin Stimulation: Strengthens skin structure for long-term firmness.
- Deep Hydration: Improves skin moisture balance for plumpness.
- Elasticity Renewal: Enhances skin resilience against aging.
- Wrinkle Softening: Reduces fine lines and smooths texture.
- Delicate Area Rejuvenation: Especially effective for under-eye wrinkles and fragile skin.
- Natural & Progressive Results: Improves skin health without artificial volume.
Ideal Candidates
The Nucleofill Revitalizing Injection is suitable for:
- Adults in their 30s–60s experiencing early or moderate signs of aging.
- Patients with dryness, dull skin, or loss of elasticity.
- Individuals with fine wrinkles, under-eye hollowness, or fragile skin.
- Men and women seeking a natural alternative to fillers or surgery.
- Younger patients wanting preventive collagen and hydration care.
Possible Risks & Complications
Nucleofill injections are very safe in Korean dermatology clinics, but minor temporary effects may include:
- Redness or Swelling: Fades within 1–3 days.
- Small Bumps at Injection Sites: Common, resolve in 24–48 hours.
- Mild Bruising or Tenderness: May last up to a week.
- Very Rare Risks: Allergic reaction or uneven texture (minimized with expert protocols).
Surgical Techniques Used
Although the Nucleofill Revitalizing Injection is non-surgical, it applies advanced injection techniques unique to Korean dermatology:
- Micro-Injection Delivery: Fine needles distribute product evenly into the dermis.
- Multi-Layer Technique: Injections at various depths for maximum repair.
- Collagen Biostimulation: Polynucleotides activate fibroblasts for long-term regeneration.
- Customized Injection Mapping: Tailored for under-eyes, cheeks, or full face.
- Combination Protocols: Frequently paired with Shurink HIFU, Thermage FLX, or threads for full-face rejuvenation.
Recovery & Aftercare
- Immediately After: Mild swelling, bumps, or redness.
- 1–3 Days: Skin calms, hydration visibly improves.
- 2–4 Weeks: Fine lines soften, texture looks smoother.
- 2–6 Months: Maximum revitalization as collagen and elastin build.
- Downtime: Minimal—most patients return to daily activities immediately.
Aftercare Tips:
- Avoid alcohol, saunas, and vigorous exercise for 48 hours.
- Use hydrating and repairing creams.
- Stay well-hydrated to enhance results.
- Always wear SPF sunscreen to protect collagen renewal.
Results & Longevity
- Immediate: Improved hydration and glow.
- Short-Term (2–4 Weeks): Wrinkle reduction and smoother texture.
- Medium-Term (2–3 Months): Stronger elasticity and skin density.
- Long-Term: Results last 6–12 months, with maintenance sessions recommended once or twice a year.
Treatment Process in Korea
Consultation & Skin Analysis – Dermatologist examines skin hydration, wrinkles, and elasticity.
Preparation – Skin cleansing and application of numbing cream for comfort.
Nucleofill Injection Procedure – Micro-injections placed into the dermis with customized mapping (under-eyes, cheeks, forehead, or full face).
Soothing Care – Cooling masks or LED light therapy applied to reduce redness and swelling.
Follow-Up – Recommended 3–4 sessions spaced 3–4 weeks apart, with annual maintenance for optimal results.
Why Korea is a Top Destination –
- Pioneers in skin boosters and regenerative medicine.
- Unique Korean multi-layer injection techniques for natural outcomes.
- Integration with K-Beauty protocols (HIFU, Thermage, and exosome boosters).
- Affordable yet world-class expertise, trusted by international patients.
- Seoul’s global reputation as the hub for anti-aging and skin revitalization.
Cost Range
The price of Nucleofill Revitalizing Injection in Korea varies based on clinic reputation, treatment area, and number of sessions:
- Single Session: USD 300 – 650
- Full-Face Package (3–4 Sessions): USD 900 – 1,800
- Advanced Anti-Aging Package (Nucleofill + HIFU / Thermage): USD 2,000 – 3,800
- Luxury Revitalization Programs (Nucleofill + Threads + Boosters): USD 3,500 – 5,000
Additional Costs in Korea:
- Consultation Fee: USD 30 – 100
- Numbing Cream (optional): USD 20 – 50
- Aftercare Skincare (hydrating serums, repair creams, SPF): USD 50 – 200
💡 Most Korean dermatologists recommend a series of 3 sessions, spaced 3–4 weeks apart, followed by yearly maintenance for sustained results.
Popular Clinics in Korea for Nucleofill Revitalizing Injection
- Banobagi Dermatology (Seoul): Experts in collagen-stimulating skin boosters.
- Oracle Skin Clinic (Nationwide): Accessible revitalization injection programs.
- View Clinic (Seoul): Known for Nucleofill + HIFU elasticity packages.
- ID Dermatology (Seoul): Specialists in anti-aging and delicate under-eye rejuvenation.
- Chaum Wellness Center (Seoul): Luxury holistic care for revitalization and skin health.



