Treatment Overview
Plinest is an Italian-developed polynucleotide (PN) skin booster made from highly purified salmon DNA fragments, now widely used in Korean dermatology clinics. It is designed to repair, regenerate, and strengthen the skin at the cellular level. By stimulating fibroblasts, it boosts collagen and elastin production, restores elasticity, and improves skin density.
Unlike fillers, which add immediate volume, Plinest works biologically over time to rebuild skin structure, improve scars, and soften wrinkles. It belongs to the same family of Salmon DNA boosters as Rejuran Healer, Juvelook, and DNA Healer:
- Plinest: Best for elasticity, density, and skin repair.
- Salmon DNA boosters (general): Known for DNA healing, scar regeneration, and anti-aging support.
Purpose & Benefits
- Cellular Repair: PN restores damaged skin cells at the DNA level.
- Collagen & Elastin Boost: Improves firmness, elasticity, and skin thickness.
- Wrinkle Softening: Smooths fine lines and prevents early aging.
- Scar Improvement: Effective for acne scars, stretch marks, and thin skin.
- Hydration: Enhances water retention in the dermis.
- Skin Density: Thickens fragile skin for better resilience.
- Synergy with Other Salmon DNA Boosters: Pairs well with Rejuran or Juvelook for advanced repair.
Ideal Candidates
Plinest in Korea is recommended for:
- Adults in their 30s–60s with sagging skin, wrinkles, or thinning skin.
- Patients with acne scars, enlarged pores, or atrophic scars.
- Men and women comparing Plinest vs Salmon DNA boosters:
- Plinest: Best for elasticity restoration, skin density, and scar repair.
- Rejuran/Other Salmon DNA: Best for DNA-level repair, inflammation control, and hydration.
- Younger patients seeking preventive anti-aging and structural strengthening.
Possible Risks & Complications
Plinest is safe in Korea’s dermatology clinics, but mild temporary side effects may occur:
- Pinpoint Redness or Bumps: Common, fade within 24–48 hours.
- Mild Swelling or Bruising: Especially in thinner skin areas.
- Tightness or Tenderness: May last 1–2 days.
- Rare Risks: Allergic response is extremely rare due to purification process.
Techniques Used
- Micro-Injections: PN placed into the dermis for regeneration.
- Meso-Gun Delivery: Ensures even distribution with minimal pain.
- Targeted Mapping: Applied to wrinkles, scars, and thin skin areas.
- Combination Therapy: Often paired with Rejuran, Juvelook, or PRP.
- Multi-Session Protocol: Typically 3–4 treatments spaced 3–4 weeks apart.
Recovery & Aftercare
- Immediately: Small bumps, redness, or mild swelling.
- 1–3 Days: Skin calms, hydration improves.
- 2–4 Weeks: Scars fade, wrinkles soften, elasticity increases.
- Maintenance: Every 6–9 months recommended.
Aftercare Tips:
- Avoid makeup for 24 hours.
- Use SPF 50+ daily.
- Apply hydrating serums and gentle skincare.
- Avoid saunas, alcohol, or intense exercise for 1–2 days.
Results & Longevity
- Immediate: Skin feels smoother and hydrated.
- Short-Term (2–4 Weeks): Improved tone, glow, and fine line reduction.
- Medium-Term (2–3 Months): Stronger elasticity, better scar healing, and collagen remodeling.
- Long-Term: Results last 6–9 months, extended with maintenance or combined with other Salmon DNA boosters.
Treatment Process in Korea
- Consultation & Skin Analysis – Doctor assesses wrinkles, scars, and skin thickness.
- Preparation – Cleansing and numbing cream applied.
- Injection Session – Plinest delivered into the dermis via meso-gun or fine needle.
- Optional Add-On: Rejuran, Juvelook, or DNA Healer for enhanced repair.
- Post-Care: Cooling masks, LED therapy, soothing serums.
- Follow-Up: Multi-session protocol completed for maximum effect.
Why Korea is a Top Destination
- Korea is a leader in Salmon DNA-based skin boosters and regenerative therapies.
- Access to authentic, KFDA-approved Plinest and other PN boosters.
- Dermatologists specialize in customized PN protocols for scars, wrinkles, and elasticity.
- More affordable compared to Western medspas, with higher expertise.
- Seoul is globally known for scar repair, anti-aging, and skin rejuvenation treatments.
Cost Range (Detailed Breakdown)
Pricing for Plinest in Korea depends on clinic and package:
- Single Session (full face): USD 300 – 600
- 3-Session Package (recommended): USD 900 – 1,500
- Plinest + Salmon DNA Combo: USD 700 – 1,500 per session
- Luxury Anti-Aging Package (Plinest + Rejuran/Juvelook + PRP/Exosomes): USD 2,000 – 3,800
Additional Costs in Korea:
- Consultation: USD 20 – 50
- Numbing & post-care: USD 20 – 40
- Add-ons (PRP, PDO threads, exosomes): USD 200 – 800
💡 Patients often describe Plinest as the “elasticity & density booster”, while other Salmon DNA boosters are known as “DNA repair injectables.” Used together, they deliver firm, radiant, and youthful skin.
Popular Clinics
- Banobagi Dermatology (Seoul): Offers Plinest + Rejuran/Salmon DNA repair programs.
- Oracle Dermatology (Seoul): Combines Plinest with PN boosters for elasticity + glow.
- Renewme Skin Clinic (Seoul): Known for acne scar and anti-aging PN treatments.
- View Plastic & Dermatology (Seoul): Provides Plinest with PRP, threads, or exosomes.
- Chaum Anti-Aging Center (Seoul): Premium PN and Salmon DNA regeneration protocols.



