Treatment Overview
Plenhyage XL is an advanced polynucleotide (PN) skin booster developed in Italy and now widely used in Korean dermatology clinics. Made from purified salmon DNA fragments, it promotes skin repair, regeneration, and collagen stimulation. Compared to standard PN boosters, Plenhyage XL is formulated in higher concentration and larger molecular structure, designed to target advanced aging, scars, and skin laxity.
It belongs to the same family of Salmon DNA boosters such as Rejuran, Plinest, and Juvelook:
- Plenhyage XL: Best for mature skin, sagging, and deeper wrinkles.
- Other Salmon DNA boosters: Best for scars, fine lines, and general skin repair.
Korean dermatologists often combine Plenhyage XL with other boosters for multi-layer rejuvenation and structural repair.
Purpose & Benefits
- DNA Repair & Regeneration: PN helps restore damaged cells at the molecular level.
- Collagen & Elastin Stimulation: Improves firmness, elasticity, and skin density.
- Wrinkle Reduction: Smooths deeper wrinkles and folds.
- Scar & Texture Repair: Improves acne scars, surgical scars, and stretch marks.
- Skin Tightening: Effective for sagging or thinning skin.
- Hydration: Retains dermal moisture for plumper skin.
- Synergy with Other Salmon DNA Boosters: Complements Rejuran or Plinest for full-spectrum rejuvenation.
Ideal Candidates
Plenhyage XL in Korea is recommended for:
- Adults in their 30s–60s with advanced wrinkles, sagging, or skin thinning.
- Patients with acne scars, stretch marks, or sun-damaged skin.
- Men and women comparing Plenhyage XL vs Salmon DNA boosters:
- Plenhyage XL: Best for mature skin, laxity, and advanced aging repair.
- Other Salmon DNA boosters (Rejuran/Plinest/Juvelook): Best for mild to moderate scars, hydration, and early anti-aging.
- Individuals looking for preventive anti-aging in their late 20s–30s or corrective anti-aging in 40s–60s.
Possible Risks & Complications
Plenhyage XL is safe and clinically tested in Korea, but temporary effects may occur:
- Redness or Pinpoint Bumps: Fade within 24–48 hours.
- Mild Swelling or Bruising: Common after injections.
- Tightness or Tenderness: May last 1–2 days.
- Rare Risks: Allergic response is extremely rare due to purification.
Techniques Used
- Micro-Injections: PN delivered into the dermis for structural repair.
- Meso-Gun Delivery: Ensures even coverage with minimal discomfort.
- Targeted Mapping: Applied to wrinkles, sagging areas, scars, and thin skin zones.
- Combination Therapy: Often paired with Salmon DNA boosters, PRP, or exosomes.
- Multi-Session Protocol: Typically 3–4 treatments spaced 3–4 weeks apart.
Recovery & Aftercare
- Immediately: Redness, swelling, or bumps from injection.
- 1–3 Days: Skin calms; hydration and elasticity improve.
- 2–4 Weeks: Wrinkles soften, scars improve, firmness increases.
- Maintenance: Every 6–9 months recommended.
Aftercare Tips:
- Avoid makeup for 24 hours.
- Apply SPF 50+ daily.
- Use hydrating PN or HA-based serums.
- Avoid alcohol, saunas, or heavy workouts for 1–2 days.
Results & Longevity
- Immediate: Smoother, hydrated skin feel.
- Short-Term (2–4 Weeks): Brighter tone, softer wrinkles, scar healing begins.
- Medium-Term (2–3 Months): Noticeable collagen stimulation, tighter skin, improved elasticity.
- Long-Term: Results last 6–9 months, extended with maintenance or paired with other PN boosters.
Treatment Process in Korea
- Consultation & Skin Analysis – Doctor evaluates wrinkles, scars, and laxity.
- Preparation – Cleansing and numbing cream applied.
- Injection Session – Plenhyage XL injected via meso-gun or micro-needle.
- Optional Add-On: Other Salmon DNA boosters (Rejuran, Plinest, Juvelook) or PRP.
- Post-Care: Cooling mask, LED therapy, soothing serums.
- Follow-Up: Multi-session protocol repeated for maximum repair.
Why Korea is a Top Destination
- Korea is a leader in PN and Salmon DNA regenerative medicine.
- Clinics provide authentic, KFDA-approved Plenhyage XL and other PN boosters.
- Dermatologists specialize in custom PN protocols for scars, wrinkles, and skin tightening.
- Treatments are more affordable than Western medspas, with world-class expertise.
- Seoul is globally recognized for anti-aging and scar repair programs.
Cost Range (Detailed Breakdown)
Pricing for Plenhyage XL in Korea depends on session and package:
- Single Session (full face): USD 400 – 700
- 3-Session Package (recommended): USD 1,200 – 1,800
- Plenhyage XL + Salmon DNA Combo: USD 800 – 1,500 per session
- Luxury Anti-Aging Package (Plenhyage XL + Rejuran/Plinest + PRP/Exosomes): USD 2,500 – 4,000
Additional Costs in Korea:
- Consultation: USD 20 – 50
- Numbing & post-care: USD 20 – 40
- Add-ons (PDO threads, PRP, exosomes): USD 200 – 800
💡 Patients often describe Plenhyage XL as the “advanced PN booster for mature skin”, while other Salmon DNA boosters are considered “repair injectables” for younger skin or scars. Together, they provide comprehensive skin regeneration.
Popular Clinics
- Banobagi Dermatology (Seoul): Specializes in Plenhyage XL with Salmon DNA synergy.
- Oracle Dermatology (Seoul): Combines Plenhyage XL with Rejuran or Plinest for anti-aging.
- Renewme Skin Clinic (Seoul): Known for scar + laxity correction PN programs.
- View Plastic & Dermatology (Seoul): Offers Plenhyage XL with PRP or PDO threads.
- Chaum Anti-Aging Center (Seoul): Premium Plenhyage XL + Salmon DNA regeneration protocols.
