Treatment Overview
Plenhyage XL is a premium polynucleotide (PN/PNN) skin booster developed in Italy and widely used in Korea’s advanced dermatology clinics. Formulated with long-chain salmon DNA fragments, it is specifically designed for mature, sun-damaged, or thinning skin, providing powerful collagen remodeling, dermal regeneration, and elasticity restoration.
Unlike hyaluronic acid injectables, which provide only hydration or volume, Plenhyage XL works biologically to stimulate fibroblasts, rebuild the dermal matrix, and reverse structural aging.
It belongs to the PN/PNN booster family (Rejuran Healer, Rejuran HB, Plinest, Juvelook, Aestura PN):
- Plenhyage XL: Best for advanced anti-aging, deep wrinkles, and skin laxity.
- Other PN/PNN boosters: Focus on hydration, scars, pigmentation, or early prevention.
Purpose & Benefits
- DNA Repair: PN/PNN restores skin health at the molecular level.
- Collagen & Elastin Stimulation: Increases dermal density and firmness.
- Wrinkle Reduction: Improves deep wrinkles and folds.
- Skin Tightening: Lifts sagging or lax skin.
- Scar & Texture Improvement: Reduces acne scars, surgical scars, and stretch marks.
- Hydration & Radiance: Improves overall skin glow while repairing structure.
- Synergy with Other PN/PNN Boosters: Plenhyage XL targets deep regeneration, while Rejuran HB or Tone-Up focus on hydration and brightness.
Ideal Candidates
Plenhyage XL in Korea is recommended for:
- Adults in their 30s–60s with deep wrinkles, sagging, or mature skin.
- Patients with thinning, sun-damaged, or scarred skin.
- Men and women comparing Plenhyage XL vs other PN/PNN boosters:
- Plenhyage XL: Best for mature skin and structural anti-aging.
- Plinest: Best for elasticity and moderate aging.
- Rejuran Healer: Best for DNA repair and barrier strengthening.
- Rejuran HB: Best for hydration + repair.
- Juvelook PN: Best for scar correction and collagen stimulation.
- Those seeking a powerful corrective anti-aging treatment.
Possible Risks & Complications
Plenhyage XL is safe and clinically proven in Korea, but temporary side effects may include:
- Redness or Pinpoint Bumps: Common, fade within 24–48 hours.
- Mild Swelling or Bruising: More likely in thinner or mature skin.
- Tenderness or Tightness: Usually resolves within 1–2 days.
- Rare Risks: Uneven absorption or irritation, minimized by expert dermatologists.
Surgical Techniques Used
Though non-surgical, Plenhyage XL requires specialized dermatology techniques for optimal results:
- Micro-Injections: PN/PNN delivered into the dermis for deep regeneration.
- Meso-Gun Delivery: Provides even coverage with minimal discomfort.
- Targeted Mapping: Focus on deep wrinkles, sagging zones, or scars.
- Layered Application: Often paired with Rejuran, Plinest, or PRP for multi-level repair.
- Multi-Session Protocol: Typically 3–4 treatments spaced 3–4 weeks apart, followed by maintenance every 6–9 months.
Recovery & Aftercare
- Immediately: Redness, mild swelling, or bumps.
- 1–3 Days: Skin calms, hydration improves.
- 2–4 Weeks: Wrinkles soften, elasticity and texture improve.
- Maintenance: Every 6–9 months recommended.
Aftercare Tips:
- Avoid makeup for 24 hours.
- Apply SPF 50+ daily.
- Use hydrating PN/HA-based serums.
- Avoid alcohol, saunas, and heavy exercise for 1–2 days.
Results & Longevity
- Immediate: Plumper, fresher skin.
- Short-Term (2–4 Weeks): Improved glow, smoother texture, reduced wrinkles.
- Medium-Term (2–3 Months): Collagen remodeling increases elasticity and firmness.
- Long-Term: Results last 6–9 months, extended with maintenance sessions.
Treatment Process in Korea
- Consultation & Skin Analysis – Doctor evaluates wrinkles, sagging, and elasticity.
- Preparation – Cleansing and numbing cream applied.
- Injection Session – Plenhyage XL injected via meso-gun or micro-needle.
- Optional Add-On: Rejuran, Juvelook, or PRP for multi-layer rejuvenation.
- Post-Care: Cooling masks, LED light therapy, soothing serums.
- Follow-Up: Multi-session plan for long-lasting results.
Why Korea is a Top Destination
- Korea is a leader in PN/PNN skin booster treatments.
- Clinics provide authentic, KFDA-approved Plenhyage XL and other PN injectables.
- Dermatologists specialize in deep anti-aging and multi-layer PN protocols.
- More affordable than Western medspas, with world-class expertise.
- Seoul is internationally recognized for anti-aging and regenerative dermatology.
Cost Range (Detailed Breakdown)
Pricing for Plenhyage XL in Korea varies depending on clinic and package:
- Single Session (full face): USD 400 – 700
- 3-Session Package (recommended): USD 1,200 – 1,800
- Plenhyage XL + PN Combo: USD 800 – 1,500 per session
- Luxury Anti-Aging Package (Plenhyage XL + Rejuran/Plinest + PRP/Exosomes): USD 2,500 – 4,000
Additional Costs in Korea:
- Consultation: USD 20 – 50
- Numbing & post-care: USD 20 – 40
- Add-ons (PDO threads, PRP, exosomes): USD 200 – 800
💡 Patients often call Plenhyage XL the “advanced density and elasticity booster”, while other PN boosters focus on scars, hydration, or pigmentation. Together, they provide a complete rejuvenation system.
Popular Clinics
- Banobagi Dermatology (Seoul): Known for Plenhyage XL + PN anti-aging programs.
- Oracle Dermatology (Seoul): Offers Plenhyage XL with Healer or Plinest for multi-layer repair.
- Renewme Skin Clinic (Seoul): Specialized in PN-based scar and laxity correction.
- View Plastic & Dermatology (Seoul): Combines Plenhyage XL with PRP/exosomes.
- Chaum Anti-Aging Center (Seoul): Premium mature skin and regeneration packages.
