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Treatment Overview

Rejuran S is a specialized PN (polynucleotide) skin booster developed specifically for acne scar treatment. Offered widely in Korean dermatology clinics, it differs from the standard Rejuran Healer by having a more concentrated and viscous formulation, allowing it to target atrophic scars with greater precision.

Derived from salmon DNA, Rejuran S stimulates fibroblast activity, collagen remodeling, and tissue regeneration. It is commonly used as an injectable treatment for rolling, boxcar, and shallow icepick scars, and is often combined with Juvelook, lasers, microneedling, or subcision for enhanced results.


Purpose & Benefits

  • Scar Remodeling: Promotes fibroblast activity and collagen deposition to lift depressed scars.
  • Skin Healing: Accelerates tissue repair and regeneration.
  • Pigmentation Control: Reduces PIH (post-inflammatory hyperpigmentation) following acne.
  • Texture Refinement: Smooths rough surfaces and minimizes pore visibility.
  • Inflammation Reduction: Calms redness and irritation associated with acne damage.
  • Combination Advantage: Works synergistically with Juvelook and exosomes for optimal outcomes.

Ideal Candidates

Rejuran S in Korea is recommended for:

  • Patients with atrophic acne scars (rolling, boxcar, mild icepick).
  • Individuals with post-acne pigmentation and redness.
  • Patients who experienced slow recovery or irritation from lasers alone.
  • Those seeking a regenerative, scar-focused injectable.
  • Individuals with sensitive or Asian skin needing a safe, biocompatible treatment.

Possible Risks & Complications

Rejuran S is generally safe, but mild side effects may occur:

  • Redness, swelling, or bruising at injection points.
  • Pinpoint bumps that resolve within 1–3 days.
  • Mild tenderness or itching during recovery.
  • Rare nodules or unevenness if injected too superficially.
  • Low risk of PIH, minimized with strict aftercare and sun protection.

Surgical Techniques Used

  • Injection Method: Direct microinjections into depressed scars or dermis.
  • Formulation: Concentrated PN (polynucleotides) for scar repair.
  • Combination Therapy: Often paired with Juvelook, fractional CO₂ lasers, RF microneedling, or subcision for deeper scars.
  • Protocol: Typically 3–4 sessions, spaced 4–6 weeks apart. Maintenance suggested annually.

Recovery & Aftercare

  • Immediately: Redness, mild swelling, or small bumps at injection sites.
  • 1–3 Days: Skin begins to calm, texture feels smoother.
  • 1 Week: Noticeable improvement in hydration and tone.
  • 1–6 Months: Progressive collagen remodeling reduces scar depth.

Aftercare Tips:

  • Avoid makeup for 24–48 hours post-injection.
  • Keep skin moisturized with barrier creams.
  • Avoid acids, scrubs, and retinoids for 5–7 days.
  • Apply SPF 50+ sunscreen daily.
  • Avoid hot baths, saunas, and strenuous workouts for 1–2 days.

Results & Longevity

  • After 1 Session: Skin feels calmer, scars slightly softened.
  • After 2 Sessions: Visible reduction in scar depth and redness.
  • After 3–4 Sessions: Long-term improvement in scar remodeling and overall skin quality.
  • Longevity: Results typically last 12–18 months, with maintenance every 12 months.

Treatment Process in Korea

  1. Consultation & Skin Analysis
    Dermatologist assesses scar type, depth, and pigmentation.
  2. Preparation
    Cleansing; topical numbing cream applied.
  3. Rejuran S Injection Session
    • Step 1: Rejuran S injected directly into scarred areas.
    • Step 2: Cooling therapy or LED mask applied.
    • Step 3: Optional Juvelook, exosome, or laser treatment for enhanced outcomes.

Duration: 20–40 minutes.


Why Korea is a Top Destination

  • Scar-Specific Protocols: Korea specializes in acne scar treatments with tailored boosters.
  • Safe for Asian Skin: Designed to reduce PIH and minimize downtime.
  • Integrated Programs: Rejuran S often combined with Juvelook, lasers, or RF for maximal results.
  • Regeneration-Oriented Care: Focus on natural collagen and tissue healing.
  • Affordable Scar Solutions: High-quality protocols at lower cost than Western clinics.

Cost Range (Estimated)

  • Single Rejuran S Session: USD 300 – 600
  • Rejuran S + LED/Soothing Therapy: USD 400 – 700
  • Comprehensive Scar Program (Rejuran S + Juvelook/Laser/Subcision): USD 1,200 – 2,500 per session

Example Korean Packages:

  • Standard Program (3 sessions): USD 900 – 1,500
  • Advanced Program (4 sessions with Juvelook add-on): USD 1,800 – 2,600
  • Premium Program (4 sessions with subcision + laser + boosters): USD 3,000 – 4,200

Popular Clinics in Seoul

  • Oracle Dermatology: Rejuran S injection programs for acne scar revision.
  • Banobagi Dermatology: Combination scar treatments with Rejuran S + lasers.
  • Renewme Skin Clinic: Rejuran S with microneedling and exosomes.
  • View Dermatology: Acne scar repair using Rejuran S with subcision and RF.
  • Chaum Anti-Aging Center: Premium scar protocols combining Rejuran S with Juvelook.

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