When it comes to non-surgical anti-aging and skin rejuvenation treatments in Korea, two of the most popular options are Rejuran Healer and Skin Boosters (such as hyaluronic acid-based injections). Both are injectable treatments that promise radiant, youthful skin, but they differ significantly in terms of ingredients, mechanisms, and outcomes.
In this guide, we’ll break down the key differences between Rejuran Healer and Skin Boosters based on Korean dermatologists’ clinical experience, helping you determine which treatment best suits your skin concerns.
🔬 What Is Rejuran Healer?
Rejuran Healer is an injectable skin rejuvenation treatment made with polynucleotides (PN), which are derived from salmon DNA. This powerful molecule is known for its:
- Cell regeneration properties
- Wound healing stimulation
- Anti-inflammatory effects
How It Works:
- Polynucleotides improve the skin’s internal healing environment by stimulating fibroblasts to produce collagen and elastin.
- Unlike fillers or hyaluronic acid, Rejuran focuses on skin quality improvement, not volume.
- Works gradually, with results becoming noticeable over 2–4 weeks.
Common Korean Uses:
- Post-laser skin repair
- Fine lines and wrinkles
- Red, sensitive, or damaged skin
- Enlarged pores and dull texture
💧 What Are Skin Boosters?
Skin boosters are injectable treatments that hydrate the skin from within. Most are made with hyaluronic acid (HA)—a naturally occurring molecule that binds water and gives skin a plump, smooth appearance.
How They Work:
- Tiny droplets of HA are injected across the face (or neck, décolleté, or hands).
- They attract and retain water in the dermis, resulting in hydrated, glowing skin.
- Some newer skin boosters include vitamins, amino acids, or antioxidants for added benefits.
Common Types in Korea:
- Juvéderm Volite
- Restylane Vital
- Chanel Injection (Filorga NCTF)
- Exosome skin boosters
- Skin booster with PDRN (similar to Rejuran-lite)
Common Korean Uses:
- Dry, dehydrated skin
- Lack of glow or radiance
- Texture irregularities
- First signs of aging
🩺 Korean Dermatologists’ Clinical Perspective
🔍 1. Main Goal: Repair vs. Hydration
“We recommend Rejuran for patients who have sensitive, red, or aging skin that needs deep repair. For dull or dry skin without inflammation, skin boosters offer faster glow and hydration.”
— Dr. Kim Ji-Hyun, Dermatologist at Gangnam Anti-Aging Clinic
- Rejuran Healer is regenerative: Think of it as “skin rehab.”
- Skin Boosters are hydrating and plumping: Think of it as a “skin pick-me-up.”
🔍 2. Speed of Results
“Skin boosters offer visible radiance within days, while Rejuran’s results build slowly over time—but they are longer-lasting and foundational.”
— Dr. Lee Sang-Woo, Dermatology Professor, Seoul
- Skin Boosters: Immediate glow (within 3–5 days), lasts 1–3 months.
- Rejuran: Takes 2–4 weeks to show, full effect in 3 months, lasts 6 months+.
🔍 3. Treatment Frequency
| Treatment | Initial Protocol | Maintenance |
|---|---|---|
| Rejuran Healer | 3 sessions every 2–4 weeks | Every 6 months |
| Skin Boosters | 1–3 sessions every 3–4 weeks | Every 3–6 months |
🔍 4. Pain, Downtime & Side Effects
“Rejuran tends to be more painful and can cause more swelling due to its viscosity. Skin boosters are more comfortable, especially with cannula techniques.”
— Dr. Park Eun-Ji, Seoul Aesthetic Clinic
- Rejuran: More stinging and swelling for 1–2 days
- Skin Boosters: Mild redness, minimal swelling
🔄 Comparison Table: Rejuran vs. Skin Boosters
| Feature | Rejuran Healer | Skin Boosters |
|---|---|---|
| Main Ingredient | Polynucleotide (PN) from salmon DNA | Hyaluronic Acid (HA) |
| Goal | Regeneration, healing, collagen stimulation | Hydration, radiance, smooth texture |
| Best For | Aging skin, sensitive/red skin, post-laser | Dehydrated, dull skin, early aging |
| Onset of Results | 2–4 weeks | 3–5 days |
| Pain Level | Moderate (numbing cream recommended) | Mild |
| Downtime | 1–2 days swelling | Minimal to none |
| Lasting Power | 6–12 months | 3–6 months |
| Clinic Preference | Anti-aging & post-procedure recovery | Skin radiance & quick refresh |
💡 Which One Is Right for You?
Choose Rejuran Healer if you:
- Have damaged, sensitive, or aging skin
- Recently had laser, microneedling, or RF
- Want to improve skin structure long-term
- Are okay with slower results for deeper repair
Choose Skin Boosters if you:
- Want an instant glow before an event
- Have dull, tired-looking skin
- Need hydration in dry or harsh climates
- Want minimal downtime with a natural finish
🧴 Can You Combine Both?
Yes! Many Korean doctors combine Rejuran and skin boosters for a dual-action approach:
“We often do Rejuran for skin structure and HA boosters for moisture in the same month, alternating sessions. It’s a beautiful synergy.”
— Dr. Choi Min-Ho, Aesthetic Dermatologist
Example protocol:
- Week 1: Rejuran injection
- Week 4: Skin booster session
- Week 7: Rejuran + mesotherapy combo (optional)
✅ Final Thoughts: Trust Your Skin to Experts
Korea’s cosmetic dermatology industry excels in both science and precision. Whether you choose Rejuran, skin boosters, or both, you’ll benefit from advanced techniques and tailored protocols that fit your unique skin profile.
To choose the right option, consult with a board-certified Korean dermatologist who can analyze your skin’s needs and recommend a plan that works with your lifestyle and goals.
