Treatment Overview
Intensive Wound-Healing-Controlled Trabeculectomy in Korea is an advanced filtration surgery designed for patients with high scarring risk or a history of trabeculectomy failure. This technique focuses on aggressively managing the wound-healing process during and after surgery using a combination of enhanced anti-fibrotic agents, biodegradable implants, postoperative modulation therapies, and AI-guided healing prediction models.
Korean glaucoma surgeons are global leaders in wound-healing–controlled filtration surgery, using MMC/5-FU micro-dosing, OCT-guided bleb imaging, and personalized fibrosis management protocols that significantly increase long-term success rates.
Purpose & Benefits
Purpose
- Prevent postoperative scarring that commonly leads to trabeculectomy failure.
- Achieve long-term, stable intraocular pressure (IOP) reduction.
- Provide strong filtration outcomes in high-risk patients.
- Reduce the need for revision surgery, additional bleb needling, or glaucoma drainage devices.
- Maintain bleb architecture through controlled tissue healing.
Benefits
- Superior Anti-Fibrotic Control: Multiple wound-healing interventions minimize scarring.
- Higher Long-Term Success Rates: Particularly in patients with aggressive fibrotic response.
- Stable, Diffuse Bleb Formation: Better shape, distribution, and long-term durability.
- Improved Outflow Predictability: Reduced risk of hypotony or filtration failure.
- Customized Healing Protocols: Korean ophthalmologists tailor wound control to each patient.
- Reduced Need for Additional Medications: Many patients experience significant drop reduction.
Ideal Candidates
Intensive Wound-Healing-Controlled Trabeculectomy in Korea is ideal for:
- Patients with moderate to severe glaucoma requiring long-term pressure control.
- Individuals with high scarring risk, including:
- Younger patients
- Patients of Asian or African descent
- History of keloids or aggressive wound healing
- Thick Tenon’s capsule
- Patients with previous failed trabeculectomy or bleb fibrosis.
- Individuals with secondary glaucoma, such as uveitic, traumatic, neovascular, or steroid-induced.
- Those needing a filtration surgery with the lowest possible risk of scarring-related failure.
Possible Risks & Complications
Although risks are lower due to intensive scar control, possible complications include:
- Conjunctival thinning
- Temporary hypotony
- Small bleb leak
- Inflammation
- Delayed wound healing
- Rare bleb-related infection
Korean clinics minimize these risks with precise anti-scarring dosimetry, close imaging-based follow-up, and personalized healing protocols.
Types of Intensive Wound-Healing-Controlled Techniques in Korea
High-Dose MMC Protocols
Customized concentration and exposure time based on healing profile.
Postoperative 5-FU Injection Series
Prevents fibroblast activity during early healing.
Biodegradable Anti-Fibrotic Implants
Placed beneath the flap to maintain space and reduce scarring.
Layered Tissue Healing Control
Multi-plane dissection reduces fibrotic contraction.
OCT-Guided Bleb Healing Monitoring
High-resolution imaging tracks healing progression.
Hybrid Anti-Fibrotic Combination Therapy
MMC + 5-FU + wound modulators used in severe-risk cases.
Collagen or Gel Spacer Placement
Prevents flap collapse and maintains diffusion space.
Surgical Techniques
AI-Based Fibrosis Prediction
Determines appropriate anti-fibrotic intensity and placement.
Customized Scleral Flap Construction
Adjusted thickness and shape for controlled aqueous flow.
Trabecular Block Excision
Creates the primary filtration pathway.
High-Precision MMC Application
Micro-dosed based on conjunctival and scleral thickness.
Implant Placement (If Needed)
Biodegradable materials maintain outflow space to prevent scarring.
Postoperative 5-FU Modulation
Applied through injections or sponge techniques.
OCT Monitoring of Wound Healing
Ensures bleb structure and filtration consistency.
Treatment Process in Korea
Step 1 – Comprehensive Evaluation
Includes OCT imaging, UBM, IOP measurement, and fibrosis risk assessment.
Step 2 – Healing-Control Strategy Planning
AI models predict the required level of scar control.
Step 3 – Intensive Wound-Healing-Controlled Trabeculectomy
Performed under local anesthesia with enhanced anti-scarring protocols.
Step 4 – Postoperative Scar Management
Includes MMC, 5-FU, or implant-based modulation as needed.
Step 5 – Long-Term Monitoring
Regular imaging ensures stable bleb formation and prevents fibrosis.
Treatment Duration: 30–60 minutes
Setting: Hospital or outpatient surgical center
Recovery & After-Care
After-Care Guidelines
- Use anti-inflammatory drops and antibiotics as instructed.
- Follow the postoperative anti-fibrotic regimen closely.
- Avoid rubbing the eye and strenuous activities.
- Protect the eye during sleep and avoid contaminated water.
- Attend all follow-up visits for wound-healing evaluation.
Recovery Timeline
- Days 1–3: Early stabilization with minimal discomfort.
- Week 1: Initial bleb formation and controlled healing begin.
- Weeks 2–4: Healing pathways monitored and adjusted if needed.
- Months 1–3: Bleb matures with low fibrosis risk.
Results & Longevity
Expected Results
- 40–70% reduction in IOP.
- Significantly improved long-term success in high-risk scarring patients.
- Diffuse, stable bleb morphology.
- Lower rates of postoperative needling or revision.
- Reduced medication dependency.
Longevity
- Results typically last 10–20+ years.
- Korean anti-fibrotic protocols extend filtration lifespan.
- Implant-assisted control further enhances durability.
Why Korea Is a Top Destination
- Global pioneers in wound-healing–controlled glaucoma surgery.
- Advanced anti-fibrotic technologies and micro-dosing systems.
- OCT-guided postoperative management ensures precise healing.
- Extremely high long-term success rates in high-risk patients.
- Comprehensive glaucoma programs for lifelong follow-up and care.
Unique Korean Innovations
- AI-driven fibrosis prediction systems.
- MMC and 5-FU micro-layered dosing algorithms.
- Real-time bleb healing analytics using OCT.
- Biodegradable anti-fibrotic implants.
- Hybrid filtration + wound-modulation protocols for extreme-risk cases.
Cost Range (Indicative Estimate)
| Procedure Type | Price (KRW) | Approx. USD | Includes |
|---|---|---|---|
| Standard Intensive Wound-Healing-Controlled Trabeculectomy | ₩4,500,000 – ₩7,000,000 | ~$3,400 – $5,300 | MMC/5-FU + surgery |
| Implant-Assisted Wound Control | ₩5,500,000 – ₩8,500,000 | ~$4,150 – $6,400 | Gel/collagen implant + anti-fibrotic care |
| Hybrid High-Risk Protocol | ₩6,500,000 – ₩9,000,000 | ~$4,900 – $6,750 | MMC + 5-FU + imaging + extended follow-up |
Popular Clinics in Korea
- B&VIIT Eye Center (Seoul) – Leaders in wound-healing–controlled filtration surgery.
- Dream Eye Center (Seoul) – Specialists in fibrosis management and MMC/5-FU protocols.
- BGN Eye Clinic (Busan & Seoul) – Experts in implant-assisted wound control.
- Glory Seoul Eye Clinic – Renowned for OCT-guided bleb monitoring.
- K-Cure Vision Center (Gangnam) – Innovators in AI-enhanced wound-healing strategies.



