Treatment Overview
Yellow-Fundus Autofluorescence (FAF) Imaging in Korea is a non-invasive diagnostic technique used to evaluate retinal pigment epithelium (RPE) health and detect early signs of age-related macular degeneration (AMD), macular dystrophies, and other retinal disorders. This method uses short-wavelength (blue) or yellow-light excitation to capture the natural autofluorescence emitted by lipofuscin in the RPE.
Korean eye centers are internationally recognized for integrating:
- High-resolution yellow-fundus autofluorescence imaging
- Multimodal imaging integration with OCT, OCTA, and wide-field fundus photography
- AI-assisted detection of RPE atrophy, drusen, and other AMD biomarkers
- Serial imaging for longitudinal monitoring of macular degeneration progression
- Rapid outpatient imaging with minimal discomfort
This program allows early detection of AMD-related changes, accurate monitoring, and personalized treatment planning.
Purpose & Benefits
Purpose
- Detect early retinal pigment epithelium changes and drusen deposits
- Monitor progression of AMD and other macular disorders
- Identify areas of RPE atrophy or dysfunction
- Provide baseline and longitudinal imaging for treatment planning
- Support decisions for anti-VEGF therapy, laser treatment, or low-vision rehabilitation
Benefits
- Non-invasive, safe, and quick procedure
- High-contrast visualization of RPE and lipofuscin accumulation
- AI-assisted analysis enhances accuracy and consistency
- Early detection of AMD progression reduces risk of vision loss
- Integration with OCT/OCTA and wide-field imaging for comprehensive assessment
- Suitable for repeated monitoring without radiation exposure
Ideal Candidates
Yellow-Fundus Autofluorescence Imaging in Korea is ideal for:
- Patients with early, intermediate, or advanced AMD
- Individuals with macular dystrophies or hereditary retinal disease
- High-risk patients with family history of AMD
- Patients undergoing anti-VEGF therapy or other retinal treatments
- Individuals requiring longitudinal monitoring of RPE health
Possible Risks & Complications
Yellow-FAF imaging is non-invasive and very safe. Potential considerations include:
Minor/Transient Issues
- Temporary glare or light sensitivity during imaging
- Mild discomfort from maintaining fixation
Minimal Risks
- Rare motion artifacts in uncooperative patients
- Very rare adverse reactions if combined with fluorescein or ICG angiography
Korean clinics minimize risks through:
- Skilled imaging technicians
- Eye-tracking and motion correction software
- AI-assisted image quality assessment
Related Diagnostic & Treatment Techniques
- Fundus Autofluorescence (FAF) – Primary method for visualizing RPE and lipofuscin
- Optical Coherence Tomography (OCT) – Structural imaging of retina layers
- OCT Angiography (OCTA) – Non-invasive vascular mapping
- Wide-Field Fundus Photography – Captures peripheral retinal changes
- Fluorescein and Indocyanine Green Angiography – Assess retinal and choroidal perfusion
- Integration with Anti-VEGF Therapy – Guides treatment timing
- Low-Vision Rehabilitation – Supports functional vision when AMD progresses
Treatment Process in Korea
Step 1 – Baseline Assessment
- Comprehensive eye examination including visual acuity and OCT
- Identification of drusen, RPE atrophy, or hyperautofluorescence regions
Step 2 – Yellow-FAF Imaging
- High-resolution imaging with yellow-light excitation
- Capture of central and peripheral retinal autofluorescence
- Optional combination with wide-field FAF for broader coverage
Step 3 – AI-Assisted Analysis
- Automated detection of abnormal autofluorescence patterns
- Quantification of atrophic or hyperautofluorescent areas
- Comparison with previous images for progression monitoring
Step 4 – Clinical Correlation
- Review by retinal specialists to guide interventions or follow-up
- Integration with OCT/OCTA findings for comprehensive assessment
Step 5 – Follow-Up Monitoring
- Regular imaging intervals (every 3–12 months depending on risk)
- Adjustment of treatment or rehabilitation plans based on progression
Duration: 10–20 minutes per session
Setting: Advanced retinal imaging clinic or ophthalmology center
Recovery & After-Care
After-Care Guidelines
- No downtime; patients can resume normal activities immediately
- Maintain follow-up appointments for longitudinal monitoring
- Continue systemic disease management (blood sugar, blood pressure)
Recovery Timeline
- Immediate: Images available instantly
- Short-Term: Retinal specialist review guides care decisions
- Long-Term: Serial FAF monitoring ensures early detection of AMD progression
Results & Longevity
Expected Results
- Detailed visualization of RPE health and lipofuscin accumulation
- Early detection of drusen and RPE atrophy
- Quantitative mapping for treatment planning
- Improved ability to monitor AMD progression and response to therapy
Longevity
- Safe for repeated use over years for lifelong monitoring
- AI-assisted longitudinal analysis enhances early intervention and outcome prediction
Why Korea Is a Top Destination
- Advanced yellow-fundus autofluorescence imaging systems
- AI-assisted analysis for accurate RPE and macular evaluation
- Experienced retinal specialists for interpretation and treatment guidance
- Integration with multimodal imaging (OCT, OCTA, wide-field imaging)
- Rapid outpatient imaging with minimal patient discomfort
- Personalized follow-up schedules for AMD patients
Unique Korean Innovations
- AI-assisted autofluorescence lesion detection and quantification
- Wide-field yellow-FAF imaging for peripheral retina assessment
- Integration with OCT/OCTA and anti-VEGF therapy planning
- Digital dashboards for longitudinal monitoring and patient management
- Telemedicine options for remote review and follow-up
Cost Range (Indicative Estimate)
| Package | Price (KRW) | Approx. USD | Inclusions |
|---|---|---|---|
| Yellow-FAF Imaging | ₩150,000 – ₩300,000 | ~$115 – $230 | High-resolution FAF + AI-assisted report |
| FAF + OCT/OCTA Comprehensive Scan | ₩400,000 – ₩700,000 | ~$310 – $540 | Central + peripheral retinal imaging with vascular mapping |
| FAF with Wide-Field Imaging | ₩500,000 – ₩900,000 | ~$380 – $700 | Ultra-widefield FAF + multimodal analysis |
| Serial Monitoring Package | ₩900,000 – ₩1,500,000 | ~$700 – $1,150 | 3–5 imaging sessions over 3–6 months with AI-assisted analysis |
Popular Clinics in Korea
- B&VIIT Eye Center (Seoul)
- Dream Eye Center (Seoul)
- BGN Eye Clinic (Seoul & Busan)
- Kim’s Eye Hospital (Seoul)
- Seoul National University Hospital Retina Center
- NUNE Eye Hospital (Daegu)
- Glory Seoul Eye Clinic
- Gangnam Severance Hospital Ophthalmology
