Treatment Overview
The 4Kscore Test is an advanced blood test that evaluates a man’s risk of aggressive prostate cancer. It measures four prostate-specific kallikrein protein levels—total PSA, free PSA, intact PSA, and human kallikrein 2 (hK2)—and combines these with clinical information such as age, DRE results, and prior biopsy history to generate a personalized risk score.
In Korea, the 4Kscore test is performed in state-of-the-art laboratories and interpreted by experienced urologists to provide precise guidance on whether a prostate biopsy is necessary, minimizing unnecessary procedures for international patients.
Purpose & Benefits
The 4Kscore Test is used to:
- Assess the probability of clinically significant prostate cancer
- Reduce unnecessary prostate biopsies in low-risk men
- Guide personalized prostate cancer screening and monitoring
Benefits include:
- Highly accurate risk assessment beyond PSA alone
- Minimally invasive with only a blood sample required
- Supports targeted decision-making for biopsy or imaging
- Reduces patient anxiety and unnecessary interventions
- Rapid results suitable for international patient planning
Ideal Candidates
The 4Kscore Test is recommended for men who:
- Have borderline or elevated PSA levels
- Had a previous negative biopsy but persistent clinical suspicion
- Are considered high-risk due to family history or genetics
- Need personalized guidance before deciding on prostate biopsy
- Are monitoring prostate health under active surveillance
Korean urologists review each patient’s clinical profile to determine if the 4Kscore test is appropriate.
Possible Risks & Complications
The 4Kscore Test is safe with minimal risk. Considerations include:
- Mild discomfort from blood draw
- Rare bruising at the puncture site
- Anxiety while awaiting results
- Interpretation may be influenced by recent infection, prostate manipulation, or medications
Techniques & Technology Used
Korean laboratories utilize advanced techniques for the 4Kscore Test:
- Immunoassays for four kallikrein markers (total PSA, free PSA, intact PSA, hK2)
- Incorporation of clinical parameters such as age, DRE, and prior biopsy
- Calculation of personalized 4Kscore to estimate risk of aggressive prostate cancer
- Certified laboratories with international quality standards
- Electronic reporting for international patients
These technologies ensure accurate and actionable results.
Treatment Process in Korea
- Consultation & Evaluation – Review PSA levels, family history, and previous biopsies
- Blood Sample Collection – Venipuncture performed under sterile conditions
- Laboratory Analysis – Measurement of kallikrein markers and calculation of 4Kscore
- Result Interpretation – Typically available within 1–3 days
- Follow-Up Recommendations – Guidance on biopsy, mpMRI, or active surveillance based on 4Kscore results
Medical tourism coordinators assist international patients with scheduling, translation, and follow-up care.
Recovery & After-Care
- No significant recovery required
- Resume normal activities immediately
- Mild soreness or bruising at the blood draw site may occur
- Maintain a record of results for future consultations or monitoring
Results & Interpretation
The 4Kscore Test provides:
- Personalized risk score (%) indicating likelihood of aggressive prostate cancer
- Guidance on the necessity of biopsy or further imaging
- Support for active surveillance or early intervention decisions
- Integration with other diagnostics such as PHI, mpMRI, or DRE
Results help patients and urologists make informed decisions for prostate health management.
Why Korea Is a Top Destination
- Advanced laboratories with international certification
- Experienced urologists for accurate interpretation and counseling
- Fast, reliable testing suitable for international patients
- Integration with mpMRI, PHI, and fusion biopsy for comprehensive prostate care
- English-language support and medical tourism assistance
- Affordable and high-quality compared to Western countries
Cost Range
Typical costs for the 4Kscore Test in Korea:
₩400,000 – ₩1,000,000 KRW (~$300–$800 USD)
Costs may vary depending on:
- Hospital or clinic grade
- Consultation fees
- Combination with other diagnostic tests (PSA, PHI, mpMRI)
Popular Clinics in Korea
- Seoul National University Hospital – Advanced Prostate Screening Center
- Samsung Medical Center – 4Kscore & Urology Diagnostics
- Asan Medical Center – Urology & Laboratory Department
- Gangnam Severance Hospital – International Patient Screening Services
- Korea University Anam Hospital – 4Kscore Test & Prostate Health
- JK Urology & Men’s Health Clinics – 4Kscore Testing & International Support
