Treatment Overview
Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) in Korea is a sophisticated corneal transplant technique that replaces only the damaged endothelial layer of the cornea — the thin, innermost cell layer responsible for maintaining corneal clarity. It is primarily performed for patients with advanced keratoconus, corneal edema, or endothelial dysfunction, providing vision restoration without full-thickness corneal replacement.
In Korea, DSAEK is performed using automated microkeratome dissection, AI-guided graft positioning, and femtosecond laser assistance to ensure a smooth and perfectly aligned graft interface. This minimally invasive approach results in faster recovery, reduced rejection risk, and improved visual clarity compared to traditional corneal transplants.
DSAEK in Korea combines precision microsurgery, regenerative therapy, and advanced imaging systems to restore vision with safety, stability, and long-term success.
Purpose & Benefits
Purpose
- Replace diseased or dysfunctional corneal endothelial cells.
- Restore corneal transparency and visual clarity.
- Strengthen corneal structure in advanced keratoconus cases involving endothelial damage.
- Eliminate corneal swelling and irregularity.
- Achieve natural, lasting visual rehabilitation.
Benefits
- Selective Replacement: Only the innermost corneal layer is replaced.
- Low Rejection Risk: Minimal immune exposure and faster adaptation.
- Automated Precision: Ensures consistent graft thickness and shape.
- Faster Visual Recovery: Quicker stabilization compared to full corneal transplants.
- Minimal Surface Disturbance: Reduces postoperative discomfort.
- Long-Term Clarity: High success rate with sustained transparency and vision.
Ideal Candidates
DSAEK in Korea is ideal for:
- Patients with advanced keratoconus affecting the endothelial layer.
- Individuals with Fuchs’ dystrophy, bullous keratopathy, or post-surgical endothelial failure.
- Those requiring partial-thickness corneal transplantation for faster recovery.
- Patients seeking a safer alternative to full corneal grafting.
- Individuals who value long-term clarity and low rejection risk.
Possible Risks & Complications
DSAEK is one of the safest and most widely performed endothelial keratoplasty procedures. However, some temporary or rare complications may occur:
- Mild Blurred Vision or Redness: Common during early healing stages.
- Light Sensitivity: Typically improves with UV-protective eyewear.
- Partial Graft Detachment: Corrected with a brief air-bubble reattachment procedure.
- Swelling or Inflammation: Controlled with medicated drops.
- Infection (Very Rare): Prevented through sterile technique and antibiotic care.
Korean ophthalmologists utilize intraoperative OCT imaging, AI-calibrated depth control, and real-time air/gas fixation systems to ensure optimal graft alignment and stability.
Techniques & Technology Used
Core Techniques
- Automated Microkeratome Graft Preparation: Produces a uniform donor graft for precision placement.
- Descemet Stripping: Removes the patient’s damaged endothelial layer with minimal trauma.
- Endothelial Graft Insertion: Donor tissue is inserted and positioned through a small incision.
- Air/Gas Bubble Fixation: Used to secure the graft against the corneal surface.
- AI-Guided Alignment Systems: Ensures exact centration and attachment of the graft.
- Regenerative Healing Therapy: Encourages rapid integration and minimizes inflammation.
These advanced technologies make Korean DSAEK among the world’s most refined and predictable corneal transplant techniques.
Treatment Process in Korea
Step-by-Step Workflow
Step 1 – Preoperative Evaluation:
Detailed corneal imaging, topography, and endothelial cell count determine candidacy and treatment parameters.
Step 2 – Surgical Planning:
AI software customizes graft thickness, curvature, and placement.
Step 3 – Anesthesia & Preparation:
Local anesthesia ensures comfort; no general anesthesia is typically required.
Step 4 – Endothelial Replacement:
The diseased endothelial layer is gently removed and replaced with a donor graft using micro-forceps and an injector system.
Step 5 – Air Bubble Fixation:
A controlled air or gas bubble holds the graft in place to promote natural adhesion.
Step 6 – Regenerative Recovery:
Healing eye drops and protective lenses support smooth recovery and corneal stability.
Procedure Duration: 45–60 minutes per eye
Recovery Period: Functional vision within 1–2 weeks; complete visual clarity in 1–2 months.
Recovery & After-Care
After-Care Guidelines
- Use antibiotic, anti-inflammatory, and lubricating drops as directed.
- Avoid rubbing or pressing on the eye for at least two weeks.
- Sleep on your back for several days to maintain graft position.
- Wear UV-protective sunglasses during recovery.
- Attend follow-up visits for imaging and graft stability monitoring.
Recovery Timeline
- Days 1–3: Mild irritation and temporary haze.
- Week 1: Vision begins to stabilize; swelling subsides.
- Weeks 2–4: Graft integration complete; clarity improves.
- 1–2 Months: Full recovery with stable, clear vision.
Results & Longevity
Expected Results
- Restored corneal clarity and transparency.
- Improved visual acuity and reduced distortion.
- Long-term stabilization of keratoconus progression.
- Natural appearance and enhanced comfort.
Longevity
DSAEK provides durable, long-term visual rehabilitation, with grafts lasting many years.
Korean clinical results show over 90–95% graft survival and transparency beyond 10 years, supported by regenerative care and advanced surgical protocols.
Why Korea Is a Top Destination
Korea is a world leader in endothelial keratoplasty and regenerative corneal surgery, offering unmatched precision, safety, and long-term outcomes.
- Automated Graft Preparation Systems: Deliver consistent, high-quality donor tissue.
- AI-Guided Surgical Visualization: Ensures precision and minimizes complications.
- Femtosecond Laser Integration: Provides unparalleled accuracy in incision and layer preparation.
- Regenerative Biologic Therapy: Promotes faster healing and graft integration.
- Expert Corneal Surgeons: Renowned for advanced lamellar and endothelial techniques.
- Comprehensive Care Programs: Include preoperative evaluation, surgery, and structured follow-up care.
Unique Korean Methods & Technology
- Automated Microkeratome Graft Systems
- AI-Calibrated Endothelial Alignment
- Femtosecond Laser-Assisted Keratoplasty
- Real-Time OCT Imaging & Air-Bubble Fixation
- Regenerative Biologic Recovery Protocols
- UV-Protective and Long-Term Stability Care
These innovations make Descemet Stripping Automated Endothelial Keratoplasty in Korea one of the most advanced, precise, and effective treatments for restoring corneal clarity in keratoconus and endothelial diseases.
Cost Range
| Treatment Package | Price (KRW) | Approx. USD | Inclusions |
|---|---|---|---|
| Standard DSAEK Surgery | ₩4,500,000 – ₩6,000,000 per eye | ~$3,200 – $4,300 | Automated graft procedure with standard aftercare |
| Laser-Assisted DSAEK | ₩6,500,000 – ₩8,000,000 per eye | ~$4,700 – $5,800 | Femtosecond-assisted graft with enhanced alignment |
| Premium Regenerative DSAEK Package | ₩9,000,000 – ₩11,000,000+ per eye | ~$6,500 – $7,900+ | AI-guided endothelial keratoplasty with regenerative recovery and long-term monitoring |
Pricing varies by clinic technology, graft source, and surgeon expertise.
Popular Clinics in Korea
- B&VIIT Eye Center (Seoul): Specializes in AI-assisted DSAEK with regenerative corneal therapy.
- Dream Eye Center (Seoul): Renowned for femtosecond and microkeratome DSAEK precision.
- BGN Eye Clinic (Busan & Seoul): Offers automated endothelial transplantation with long-term graft success.
- Glory Seoul Eye Clinic: Expert in minimally invasive lamellar grafting and biologic healing.
- K-Cure Vision Center (Gangnam): Pioneers in AI-guided DSAEK and advanced corneal rehabilitation programs.
