Treatment Overview
The Diurnal IOP Fluctuation Testing Program in Korea is a specialized glaucoma diagnostic service designed to measure and track intraocular pressure (IOP) variations throughout the day. Since glaucoma progression is strongly influenced not only by average IOP but also by daily pressure swings, diurnal testing provides essential insights that cannot be obtained from a single clinic reading.
Korean glaucoma centers are globally recognized for their advanced diurnal IOP evaluation systems, integrating:
- Multiple daytime IOP measurements
- Rebound tonometry and non-contact tonometry
- High-precision Goldmann applanation readings
- AI-based fluctuation pattern analysis
- Corneal-compensated pressure calculations
- Trend mapping for treatment response evaluation
By identifying pressure peaks and instability patterns, this program enables ophthalmologists to adjust treatment strategies for optimal long-term glaucoma control.
Purpose & Benefits
Purpose
- Detect harmful daytime IOP spikes
- Identify unpredictable IOP fluctuations that may damage the optic nerve
- Assess medication effectiveness and timing
- Guide decision-making for laser therapy or MIGS
- Improve the accuracy of glaucoma risk staging
- Evaluate IOP stability under real-life conditions
Benefits
- Highly accurate evaluation of pressure variations over a full day
- Early detection of pressure instability, even with normal single readings
- Improved treatment outcomes through personalized adjustment
- Enhanced accuracy for planning SLT, MIGS, or filtration surgery
- Better long-term optic nerve protection
- More effective medication scheduling based on real IOP behavior
- Essential for normal-tension glaucoma, where spikes are often hidden
Ideal Candidates
The Diurnal IOP Fluctuation Testing Program in Korea is ideal for:
- Patients with normal-tension glaucoma (NTG)
- Individuals with progressive glaucoma despite “normal” clinic readings
- Patients experiencing visual field loss with unexplained causes
- Individuals needing medication timing optimization
- Patients with suspected IOP spikes
- Individuals being evaluated for laser therapy or MIGS
- New glaucoma patients requiring baseline pressure patterns
Possible Risks & Complications
The test is safe, non-invasive, and well tolerated. Mild temporary effects may include:
- Minor irritation from repeated tonometry
- Slight redness after multiple measurements
- Anxiety-related IOP variability (rare)
- Overinterpretation without correlation to clinical exams
Korean specialists reduce risks through:
- Careful calibration of devices
- Corneal-compensation adjustments
- AI-enhanced interpretation to avoid misleading peaks
- Continuous correlation with OCT and visual field data
Surgical Techniques
(These procedures are considered when diurnal IOP testing reveals significant fluctuations or uncontrolled peaks.)
1. Selective Laser Trabeculoplasty (SLT)
Recommended when trabecular resistance causes afternoon or morning spikes.
2. MicroPulse Laser Therapy
Useful for lowering peaks without damaging surrounding tissues.
3. MIGS (Minimally Invasive Glaucoma Surgery)
Indicated for persistent fluctuations:
- iStent Inject
- Hydrus Microstent
- KDB goniotomy
- Canaloplasty
- GATT
- Trabecular micro-bypass procedures
4. Filtration Surgery
Used in advanced cases:
- Trabeculectomy
- PreserFlo MicroShunt
- Tube implants
5. Medication Timing Optimization
Dosing may be adjusted to target the hours when IOP peaks naturally.
Treatment Process in Korea
Step 1 – Baseline Eye Examination
Includes OCT, visual fields, optic nerve evaluation, and initial IOP screening.
Step 2 – Scheduled IOP Readings
IOP is measured at various times of day (e.g., morning, midday, afternoon, evening) using Goldmann applanation or rebound tonometry.
Step 3 – Corneal Compensation
Measurements are corrected for corneal thickness and biomechanics.
Step 4 – AI-Based Fluctuation Analysis
Pressure peaks, irregular patterns, and diurnal slopes are analyzed by advanced software.
Step 5 – Treatment Adjustment
Medication schedules, laser therapy, or MIGS may be recommended based on results.
Testing Duration: 1 day (multiple visits or on-site monitoring)
Setting: Outpatient glaucoma diagnostic center
Recovery & After-Care
After-Care Guidelines
- Resume normal daily activities
- Use lubricating drops if minor irritation occurs
- Follow treatment change instructions
- Attend follow-up visits for long-term monitoring
- Report symptoms such as sudden blurred vision or pain
Recovery Timeline
Immediately: Return to normal activities after final measurement
Days 1–3: Any mild irritation resolves
Week 1: Treatment adjustments begin to show results
1–3 Months: Long-term IOP stability evaluated
Results & Longevity
Expected Results
- Detection of previously hidden pressure spikes
- Accurate understanding of daily IOP behavior
- Better prediction of glaucoma progression
- Improved optic nerve protection
- More effective treatment plans and medication timing
Longevity
- Diurnal testing is often repeated annually or after adjusting therapy
- Helps maintain accurate long-term disease management
- Provides critical data for lifelong glaucoma stability
- AI trend tracking continues to enhance predictive accuracy
Why Korea Is a Top Destination
- Highly advanced glaucoma diagnostic centers
- Comprehensive pressure analysis using AI tools
- Precise measurements with calibrated tonometry systems
- Unmatched expertise in NTG and pressure variability
- Seamless integration with other glaucoma programs
- Excellent long-term patient outcomes
Unique Korean Innovations
- AI-powered diurnal IOP fluctuation modeling
- Customized pressure-stabilization medication schedules
- Corneal biomechanics-integrated IOP correction
- Predictive risk scoring for diurnal instability
- Diurnal IOP pattern integration into MIGS planning
- Advanced rebound tonometry with multi-point mapping
These innovations make Korea’s Diurnal IOP Fluctuation Testing Program one of the most accurate and effective tools for evaluating pressure instability in glaucoma patients.
Cost Range (Indicative Estimate)
| Program Package | Price (KRW) | Approx. USD | Inclusions |
|---|---|---|---|
| Basic Diurnal Testing Package | ₩150,000 – ₩250,000 | ~$110 – $190 | Multiple IOP readings + basic report |
| Advanced Diurnal IOP Mapping Program | ₩300,000 – ₩600,000 | ~$230 – $450 | Multi-point mapping + corneal compensation |
| Comprehensive Diurnal Analysis + Treatment Plan | ₩700,000 – ₩1,500,000+ | ~$520 – $1,100+ | AI analysis + treatment optimization + MIGS planning |
Popular Clinics in Korea
- B&VIIT Eye Center (Seoul)
- Dream Eye Center (Seoul)
- BGN Eye Clinic (Seoul & Busan)
- Glory Seoul Eye Clinic
- K-Cure Vision Center (Gangnam)



