Treatment Overview
Genetic-Screen Assisted Oocyte Freezing in Korea represents a new frontier in fertility preservation — combining advanced vitrification technology with genetic screening and oocyte health assessment to optimize egg quality before freezing. This integrated approach ensures that only genetically stable, chromosomally normal, and biologically strong oocytes are cryopreserved, maximizing the likelihood of future pregnancy success.
Korean fertility centers have pioneered this advanced egg freezing protocol by incorporating AI-powered microscopy, genetic biomarker analysis, and precision cryobiology. These technologies enable embryologists to assess egg quality not only based on visual maturity but also on genetic integrity. The result is a next-generation fertility preservation method that blends reproductive science with genomic medicine — ensuring each stored egg has the highest potential for successful fertilization and healthy embryo development.
Purpose & Benefits
The main goal of Genetic-Screen Assisted Oocyte Freezing is to preserve high-quality eggs with verified genetic health, ensuring the best outcomes for future IVF or assisted conception treatments.
Key benefits include:
- Genetic health assurance: Screening detects chromosomal abnormalities before freezing.
- Higher implantation potential: Only chromosomally normal eggs are preserved for later use.
- Reduced miscarriage risk: Pre-screening minimizes the chance of genetic-related pregnancy loss.
- Improved IVF efficiency: Increases the success rate of fertilization and embryo development.
- Personalized egg selection: Each oocyte is analyzed for quality, maturity, and genetic stability.
- Long-term fertility preservation: Genetically screened eggs remain viable for years without quality loss.
In Korea, fertility specialists integrate this genetic insight with advanced vitrification and AI tools to provide an unparalleled level of safety and precision in egg preservation.
Ideal Candidates
Genetic-Screen Assisted Oocyte Freezing in Korea is ideal for women who seek not only to preserve their fertility but also to ensure the genetic health of their future pregnancies.
Best suited for:
- Women in their 20s to late 30s who want to freeze high-quality eggs for future use.
- Patients with a family history of genetic or chromosomal disorders.
- Women planning delayed pregnancy who wish to minimize age-related genetic risks.
- Couples undergoing pre-IVF fertility planning or using donor sperm.
- Cancer patients preserving fertility before chemotherapy or radiation.
- Individuals pursuing advanced reproductive or genetic planning, including preimplantation genetic testing (PGT).
This program is particularly valuable for women who want added reassurance about genetic normalcy and future pregnancy success.
Possible Risks & Complications
Egg freezing and genetic screening are safe and non-invasive when conducted by experienced fertility professionals. However, minor risks or side effects may occur during the ovarian stimulation and retrieval phases:
- Mild bloating or discomfort from hormone stimulation.
- Minor bleeding or spotting after egg retrieval.
- Rare cases of ovarian hyperstimulation syndrome (OHSS).
- Emotional stress or anxiety associated with the fertility process.
Korean fertility centers minimize these risks through personalized medication plans, AI-monitored hormone management, and ethical genetic testing standards, ensuring a comfortable and transparent experience.
Surgical & Laboratory Techniques Used
The Genetic-Screen Assisted Oocyte Freezing process merges clinical precision with molecular-level screening, allowing only genetically viable eggs to be preserved.
Key techniques include:
- Personalized Ovarian Stimulation: Tailored hormone regimens optimize egg growth while reducing side effects.
- Ultrasound-Guided Egg Retrieval: A short, safe, outpatient procedure performed under sedation.
- Oocyte Grading & Assessment: Each retrieved egg is evaluated for maturity and cytoplasmic quality using AI-based imaging.
- Genetic Pre-Screening: Advanced non-destructive methods such as oocyte transcriptome analysis or polar body biopsy help detect chromosomal abnormalities.
- Vitrification (Ultra-Rapid Freezing): Mature, genetically normal eggs are frozen instantly to prevent ice crystal formation and preserve structural integrity.
- Cryostorage in Controlled Biobank Systems: Eggs are stored in −196°C liquid nitrogen tanks with continuous temperature monitoring and dual backup systems.
- AI Data Tracking: Integrated digital systems ensure full traceability and data integrity of each frozen egg.
Korea’s reproductive laboratories combine genomics, embryology, and cryobiology to create one of the most advanced fertility preservation ecosystems in the world.
Recovery & Aftercare
Recovery after egg retrieval is typically brief and uncomplicated. Most women resume daily activities within 24 hours.
Aftercare guidelines include:
- Resting for a few hours following the procedure.
- Avoiding intense exercise or sexual activity for 1–2 days.
- Taking prescribed hormonal medications as directed.
- Drinking plenty of fluids to prevent discomfort or bloating.
- Scheduling a follow-up consultation to discuss genetic and cryostorage results.
Korean fertility clinics emphasize post-procedure wellness, offering nutritional counseling, emotional support, and fertility health management to ensure patients remain comfortable and informed.
Results & Longevity
Genetic-Screen Assisted Oocyte Freezing in Korea provides superior long-term outcomes by ensuring that only healthy, chromosomally normal eggs are preserved.
Typical results include:
- Egg survival rate after thawing: 95–98%.
- Fertilization rate after thaw: 70–85%.
- Embryo development success: Higher due to pre-selection of genetically normal eggs.
- Reduced miscarriage risk: Up to 50% lower than cycles using untested eggs.
- Storage longevity: Eggs remain viable for 10–20 years or longer under stable cryogenic conditions.
By integrating genomic insight and vitrification excellence, Korean fertility programs achieve higher efficiency, fewer IVF cycles, and stronger pregnancy outcomes.
Treatment Process in Korea
The Genetic-Screen Assisted Oocyte Freezing process in Korea follows a comprehensive and precision-based pathway, integrating fertility preservation with genetic science.
Step 1: Consultation & Genetic Evaluation
Patients undergo fertility testing (AMH, FSH, LH) and genetic counseling to identify risks or hereditary patterns.
Step 2: Personalized Ovarian Stimulation
A tailored hormone protocol is developed based on the patient’s ovarian reserve, age, and health profile.
Step 3: Egg Retrieval
Performed under ultrasound guidance in a short outpatient procedure.
Step 4: Oocyte Grading & Genetic Screening
Mature oocytes are screened for chromosomal stability using advanced molecular diagnostics and AI-assisted quality analysis.
Step 5: Vitrification & Cryostorage
Genetically healthy eggs are vitrified using high-speed cooling and stored securely in nitrogen-based cryo systems.
Step 6: Long-Term Monitoring & Future Use
Eggs can be stored for decades and later used for IVF, with or without further genetic testing of embryos (PGT-A or PGT-M).
Why Korea Excels in Genetic-Screen Assisted Oocyte Freezing
Korea’s fertility centers lead the world in combining reproductive genetics and cryobiology. Key advantages include:
- Next-generation genomic testing platforms for accurate screening.
- AI-driven egg grading and morphological analysis.
- Automated vitrification and cryostorage systems.
- Internationally trained embryologists and genetic counselors.
- Ethically regulated genetic testing protocols.
- Affordable, world-class fertility preservation programs accessible to both domestic and international patients.
These innovations make Korea a global leader in scientifically advanced, patient-centered egg freezing.
Cost Range
The cost of Genetic-Screen Assisted Oocyte Freezing in Korea depends on the number of eggs retrieved, the type of genetic testing performed, and storage duration.
- Standard Egg Freezing Cycle: USD 3,000 – 4,500
- With Genetic Screening & AI-Assisted Selection: USD 5,500 – 7,000
- Annual Cryostorage Fee: USD 300 – 500
- Multi-Year Package (3–5 years): USD 6,000 – 8,500
These packages generally include ovarian stimulation, genetic evaluation, egg retrieval, vitrification, and one year of secure storage.
Popular Clinics
Korea’s leading fertility clinics offering Genetic-Screen Assisted Oocyte Freezing combine advanced reproductive genetics with high-precision cryotechnology.
CHA Fertility Center (Seoul & Bundang)
Globally recognized for integrating AI-driven vitrification and preimplantation genetic testing systems.
Asan Medical Center – Department of Reproductive Medicine
Offers genetic risk profiling, precision oocyte freezing, and embryo genomics.
MizMedi Women’s Hospital (Seoul)
Specializes in personalized fertility preservation and genetic counseling programs.
Hamchoon Women’s Clinic
Known for molecular-level oocyte evaluation and secure long-term cryostorage.
G Clinic (Seoul)
Provides cost-effective, patient-centered fertility preservation with integrated genomic screening.
