Treatment Overview
Glutathione IV Therapy is a popular dermatology-based aesthetic treatment in Korea used for age spots (liver spots), pigmentation, skin brightening, and overall rejuvenation. Glutathione is a powerful antioxidant naturally found in the body that regulates melanin production. When delivered intravenously, it helps reduce hyperpigmentation by inhibiting tyrosinase activity, leading to lighter, clearer, and more radiant skin.
In Korea, this therapy is often combined with laser pigmentation treatments (Spectra, Pico, Fraxel) or skin boosters (Rejuran, PN, exosomes) to maximize results.
Purpose & Benefits
- Pigmentation Control: Helps fade age spots, sunspots, and diffuse hyperpigmentation.
- Skin Brightening: Promotes a radiant, even skin tone.
- Anti-Aging Benefits: Reduces oxidative stress, improving skin elasticity.
- Detoxification: Supports liver function and immune health.
- Combination Friendly: Enhances the effects of pigmentation laser treatments.
Ideal Candidates
- Adults with age spots (liver spots) or sun-induced pigmentation.
- Patients with dull skin, uneven tone, or oxidative stress.
- Individuals who want a non-laser, systemic approach to pigmentation.
- Those undergoing laser or peel treatments, looking for boosted results.
Possible Risks & Complications
Glutathione IV therapy is generally safe when performed by licensed professionals in Korean clinics, but may include:
- Mild Reactions: Headache, nausea, or fatigue post-infusion.
- Injection Site Irritation: Redness or swelling where IV is placed.
- Allergic Reactions: Rare but possible with high doses.
- Overuse Risks: Excessive, unsupervised infusions may strain the kidneys.
Surgical Techniques Used
- Intravenous Infusion: Glutathione is delivered directly into the bloodstream for maximum absorption.
- Combination Drips: Often mixed with Vitamin C, collagen, or whitening cocktails for synergistic pigment reduction.
- Customized Dosing: Korean dermatologists tailor the dosage and frequency based on skin type and pigmentation severity.
- Adjunctive Use: Commonly paired with lasers, peels, or boosters to accelerate skin brightening.
Recovery & Aftercare
- Immediately: Most patients resume normal activities with no downtime.
- 1–2 Days: Subtle brightening effect may be noticed after the first drip.
- Ongoing: Multiple sessions required for visible fading of age spots.
Aftercare Tips:
- Stay hydrated to support detoxification.
- Apply daily SPF 50+ sunscreen to protect from UV-induced pigmentation.
- Maintain a balanced diet with antioxidants.
- Avoid excessive alcohol and smoking, which reduce therapy effectiveness.
Results & Longevity
- After 1–2 Sessions: Subtle glow and improved skin clarity.
- After 4–6 Sessions: Visible fading of age spots and overall brightening.
- Long-Term: Results last several months; maintenance infusions every 1–3 months are common in Korea.
Treatment Process in Korea
Korea is internationally recognized for advanced IV therapy protocols under dermatology and anti-aging care.
- Consultation & Skin Analysis – Assess pigmentation, sun damage, and medical history.
- Preparation – IV line placed with sterilization protocols.
- Glutathione Drip Infusion – Customized blend of glutathione, Vitamin C, and other antioxidants.
- Post-Care – Skin soothing treatments, hydration therapy, or topical whitening serums.
- Follow-Up – Typically 5–10 sessions scheduled weekly or bi-weekly.
Unique Korean Methods & Advantages:
- Combination programs with lasers (Spectra, Pico, Fraxel) + IV drips for superior age spot clearance.
- Specialized whitening drips that mix glutathione with Vitamin C, collagen, or placenta extract.
- Clinics integrate anti-aging boosters (Rejuran, PN, exosomes) alongside IV therapy.
- Korea is considered a top destination due to its integrated pigmentation protocols, affordable packages, and expertise in Asian skin care.
Cost Range (Estimated)
- Single Glutathione IV Drip: USD 80 – 200
- 5–10 Session Package: USD 500 – 1,200
- Premium Whitening Programs (IV + Laser + Boosters): USD 1,200 – 2,500
Additional Costs:
- Consultation: USD 20 – 50
- Add-ons (Vitamin C, collagen, placenta, exosomes): USD 50 – 200 per infusion
Popular Clinics in Seoul
- Oracle Dermatology: Glutathione Whitening Drips + Pico Laser for pigment.
- Banobagi Dermatology: IV therapy combined with anti-aging boosters.
- Renewme Skin Clinic: Whitening drip protocols + pigmentation laser toning.
- View Plastic & Dermatology: Glutathione IV + Fraxel for age spots + rejuvenation.
- Chaum Anti-Aging Center: Premium IV programs with glutathione, exosomes, and regenerative boosters.



