Treatment Overview
Glutathione IV Therapy is one of the most popular skin-brightening and pigmentation treatments in Korea. Glutathione, a powerful antioxidant naturally produced in the body, is delivered intravenously (IV) to promote skin lightening, reduce oxidative stress, and suppress melanin production.
In Korean dermatology clinics, Glutathione IV is often used as a supportive therapy for post-inflammatory hyperpigmentation (PIH), acne pigmentation, melasma, and overall skin radiance. It is frequently combined with Vitamin C, tranexamic acid drips, lasers (Pico/Nd:YAG), or PRP for enhanced pigment clearance and anti-aging benefits.
Purpose & Benefits
- PIH Reduction: Suppresses melanin activity to fade acne pigmentation.
- Skin Brightening: Improves overall tone, radiance, and glow.
- Antioxidant Protection: Neutralizes free radicals that worsen pigmentation.
- Melasma-Friendly: Helps reduce stubborn pigment patches when combined with lasers.
- Safe Adjunct Therapy: Enhances results of topical and laser treatments.
Ideal Candidates
Glutathione IV Therapy in Korea is recommended for:
- Patients with PIH or acne-related pigmentation seeking systemic skin brightening.
- Individuals with dull, uneven skin tone resistant to topical creams alone.
- Adults looking for supportive anti-aging and detox effects.
- Patients combining therapies (Glutathione + Vitamin C + lasers) for stronger results.
Possible Risks & Complications
Glutathione IV is generally safe, but should be administered under medical supervision:
- Mild Side Effects: Temporary bruising at injection site, mild nausea.
- Rare Risks: Allergic reaction, dizziness, or overuse-related imbalances (rare in Korean low-dose protocols).
- Contraindications: Patients with severe asthma or liver/kidney disease may need caution.
Techniques Used
- IV Drip Infusion: Glutathione mixed with Vitamin C or whitening cocktails, infused over 20–40 minutes.
- Combination Whitening Drips: Often paired with Vitamin C, collagen, or tranexamic acid.
- Adjunct Therapy: Typically combined with laser toning, PRP, or chemical peels for PIH.
Protocol: Usually 4–10 weekly or biweekly sessions, followed by maintenance every 1–3 months.
Recovery & Aftercare
Immediately: Mild warmth, refreshed feeling after infusion.
1–2 Days: Subtle glow and hydration.
1–4 Weeks: Gradual brightening and PIH reduction with repeated sessions.
Aftercare Tips:
- Maintain SPF 50+ sunscreen daily.
- Stay hydrated to support detox and skin renewal.
- Continue topical brightening agents for best synergy.
- Avoid smoking and excessive alcohol, as these reduce antioxidant efficacy.
Results & Longevity
- After 1–2 Sessions: Subtle glow and fresher tone.
- After 4–6 Sessions: Visible skin brightening, PIH starts to fade.
- After 8–10 Sessions: Noticeable reduction in pigmentation, more even tone.
- Long-Term: Results last several months; ongoing maintenance is recommended.
Treatment Process in Korea
Consultation & Screening
- Medical history reviewed (allergies, liver/kidney health).
- Treatment plan tailored for PIH severity and desired brightness.
Preparation
- IV line insertion, whitening cocktail prepared.
- Relaxing infusion setting provided.
Glutathione IV Session
- Step 1: Glutathione + Vitamin C drip infused over 20–40 minutes.
- Step 2: Optional boosters added (tranexamic acid, collagen).
- Step 3: Sunscreen and skincare recommendations given post-session.
Post-Treatment Care
- Hydration and rest encouraged.
- Strict sun protection maintained.
Follow-Up
- 4–10 sessions recommended for visible PIH clearance.
- Combined with Pico/Nd:YAG lasers, PRP, or peels for best results.
Unique Korean Advantages
- Whitening Cocktails: Korean clinics often combine glutathione with Vitamin C, collagen, or TXA.
- Holistic Packages: Bundled with lasers and topical care for comprehensive PIH management.
- Asian Skin Safety: Lower, repeated doses minimize rebound pigmentation.
- Affordable Multi-Sessions: Package pricing makes it more cost-effective than in Western countries.
Cost Range (Estimated)
- Single Session: USD 100 – 200
- 5–10 Session Package: USD 500 – 1,500
- Premium Whitening Program (Glutathione IV + Lasers/Boosters): USD 1,500 – 3,000
Additional Costs:
- Consultation: USD 20 – 50
- Skin boosters (PRP, Rejuran, exosomes): USD 200 – 500
- Add-on whitening serums: USD 80 – 150
Example Korean Packages:
- Basic Whitening IV (5 sessions): USD 400–700
- Advanced PIH Program (Glutathione IV + Pico): USD 1,200–1,800
- Premium Brightening Package (IV + PRP/Boosters + Lasers): USD 2,000–3,000
Popular Clinics in Seoul
- Oracle Dermatology: Glutathione IV + Nd:YAG for PIH.
- Banobagi Dermatology: Whitening IV + Pico for acne pigmentation.
- Renewme Skin Clinic: Whitening drips + PRP or boosters.
- View Plastic & Dermatology: Glutathione IV + Fraxel for pigment and scars.
- Chaum Anti-Aging Center: Premium whitening drip programs with regenerative add-ons.



