Treatment Overview
IUI-Plus represents the evolution of traditional Intrauterine Insemination (IUI) — enhanced through advanced reproductive technologies, precision diagnostics, and personalized hormonal management. In Korea, IUI-Plus combines standard insemination techniques with cutting-edge laboratory innovations, AI-assisted ovulation tracking, and uterine environment optimization to significantly improve pregnancy success rates.
This advanced program integrates multiple fertility strategies — such as microfluidic sperm selection, ultrasound-guided insemination, luteal phase support, and endometrial receptivity enhancement — offering patients a higher chance of conception with minimal stress and invasiveness. Korean fertility specialists are internationally known for perfecting the IUI-Plus approach through decades of research and innovation in reproductive medicine.
Purpose & Benefits
The purpose of IUI-Plus is to optimize every step of the insemination process — from sperm selection to ovulation timing — ensuring that fertilization occurs under ideal biological conditions.
Key benefits include:
- Enhanced pregnancy success rates compared to conventional IUI.
- Scientifically optimized sperm and egg interaction timing.
- Precise ovulation tracking through ultrasound and hormone mapping.
- Improved sperm quality using microfluidic or gradient sorting.
- Better uterine receptivity through personalized luteal support.
- Reduced risk of overstimulation or multiple pregnancies.
- Short treatment cycles with minimal discomfort.
IUI-Plus merges modern reproductive science with Korea’s high medical standards, offering a balanced, efficient, and patient-friendly fertility treatment.
Ideal Candidates
IUI-Plus in Korea is ideal for:
- Couples with unexplained infertility.
- Mild male-factor infertility (reduced motility or count).
- Women with ovulation irregularities or mild endometriosis.
- Patients who did not conceive through standard IUI cycles.
- Individuals preferring a less invasive alternative before IVF.
- Single women or same-sex couples using donor sperm.
Korean fertility centers perform detailed hormonal and reproductive evaluations before starting IUI-Plus, ensuring the treatment plan matches each patient’s fertility profile.
Possible Risks & Complications
IUI-Plus is a safe and minimally invasive procedure, but like all assisted reproductive treatments, minor side effects can occur:
- Mild cramping or spotting after insemination.
- Temporary bloating due to ovarian stimulation.
- Rare ovarian hyperstimulation if medication is used.
- Low risk of multiple pregnancies when several follicles develop.
Korean clinics use strict monitoring and controlled protocols to ensure patient safety and minimize any discomfort or complications.
Advanced Techniques & Technology in IUI-Plus Programs
Korea’s IUI-Plus programs utilize the latest reproductive technologies to refine every stage of the conception process.
Core techniques include:
- Microfluidic Sperm Sorting: Selects sperm with optimal motility and DNA integrity using advanced microchannel systems.
- Density Gradient Centrifugation: Purifies and concentrates motile sperm for insemination.
- Ultrasound-Guided Insemination: Ensures precise placement of sperm in the uterine cavity.
- AI-Based Ovulation Prediction: Accurately determines insemination timing based on hormonal data and imaging.
- Endometrial Receptivity Testing (ERA): Identifies the best implantation window for each patient.
- Luteal Phase Hormonal Support: Stabilizes the uterine environment for implantation.
- Minimal Stimulation Protocols: Use of low-dose fertility medications to encourage natural egg growth.
This multi-dimensional, evidence-based system is what distinguishes IUI-Plus from standard IUI cycles.
Recovery & Aftercare
Recovery after IUI-Plus is fast and uncomplicated.
Post-procedure recommendations include:
- Rest for 10–20 minutes after insemination.
- Resume normal daily activities immediately after treatment.
- Avoid strenuous exercise for 24–48 hours.
- Take prescribed luteal support medications such as progesterone or low-dose estrogen.
- Schedule a pregnancy test 14 days after insemination.
Korean fertility centers also offer holistic aftercare programs, including nutrition guidance, emotional counseling, and acupuncture, to enhance treatment success and patient well-being.
Results & Success Rates
Korea’s IUI-Plus program has shown superior outcomes compared to conventional IUI through precision, technology, and patient-tailored protocols.
- Per-cycle success rate: 20–30% for women under 35.
- Cumulative success rate (3–6 cycles): 40–60%.
- Lower cycle cancellation rates due to improved ovulation and hormonal tracking.
- Reduced need to transition to IVF in many patients.
These results reflect Korea’s leadership in integrating advanced reproductive technology with individualized care for consistently high success rates.
IUI-Plus Treatment Process in Korea
The IUI-Plus process in Korea is systematic, patient-centered, and supported by precision diagnostics:
1. Fertility Assessment & Consultation
Comprehensive testing for both partners, including hormonal profiling, semen analysis, and uterine evaluation.
2. Mild Ovarian Stimulation (if indicated)
Low-dose fertility medications may be prescribed to stimulate controlled follicle growth.
3. Ultrasound & Hormone Monitoring
Regular imaging and blood tests determine follicular maturity and ovulation timing.
4. Ovulation Trigger
An hCG or GnRH agonist trigger injection induces ovulation at the optimal moment.
5. Sperm Preparation
Sperm is washed, filtered, and processed using microfluidic or density gradient methods.
6. Insemination Procedure
Prepared sperm is gently inserted into the uterus under ultrasound guidance.
7. Luteal Support & Pregnancy Test
Progesterone therapy supports implantation, followed by a pregnancy test after 14 days.
This streamlined, evidence-based process ensures precision at every stage of the reproductive cycle.
Why Korea Leads in IUI-Plus Fertility Programs
Korea has become a global hub for fertility innovation, offering one of the most technologically advanced IUI programs in Asia.
Key reasons Korea is a top choice:
- Integration of AI and precision imaging for cycle monitoring.
- World-class fertility specialists with extensive ART experience.
- Accredited reproductive laboratories meeting international standards.
- Comprehensive fertility packages with transparent pricing.
- Multilingual care teams and seamless support for international patients.
- Strong ethical and safety regulations in assisted reproduction.
IUI-Plus in Korea exemplifies the nation’s commitment to high-quality, patient-focused reproductive medicine.
Cost Range for IUI-Plus in Korea
The cost of IUI-Plus varies depending on medication use, technology integration, and clinic facilities.
- Standard IUI-Plus Package: USD 1,200 – 2,500 per cycle.
- Advanced IUI-Plus with microfluidic sorting or AI-assisted timing: USD 2,500 – 3,500 per cycle.
- Comprehensive multi-cycle packages (3–6 cycles): Discounted rates available.
Additional costs may apply for genetic or hormonal testing, medication, and follow-up care. Despite its advanced nature, IUI-Plus remains more affordable than IVF while offering high pregnancy success rates.
Leading Clinics Offering IUI-Plus in Korea
- CHA Fertility Center (Seoul & Bundang): Global leader in next-generation IUI and reproductive technology.
- Asan Medical Center – Reproductive Medicine Department: Expert in AI-assisted ovulation and hormonal synchronization.
- MizMedi Women’s Hospital (Seoul): Known for precision insemination and holistic fertility programs.
- G Clinic (Seoul): Offers affordable IUI-Plus packages for local and international patients.
- Hamchoon Women’s Clinic: Specializes in advanced sperm preparation and endometrial optimization.
