Treatment Overview
Localized PDRN Microneedling is a regenerative acne scar treatment practiced in leading Korean dermatology clinics, designed to repair atrophic scars, uneven skin texture, and post-acne pigmentation.
This therapy combines:
- Microneedling – a device with ultra-fine needles creates controlled micro-injuries in the skin, stimulating collagen and elastin production to remodel acne scars.
- PDRN (Polydeoxyribonucleotide) – a regenerative compound derived from salmon DNA, infused directly into the dermis through microneedling channels. PDRN enhances tissue regeneration, angiogenesis, and fibroblast activity, while also reducing inflammation and pigmentation.
Localized application allows dermatologists to target specific scarred areas, maximizing scar healing while minimizing unnecessary treatment of unaffected skin.
Purpose & Benefits
- Scar Remodeling: Stimulates collagen to lift depressed scars.
- Accelerated Regeneration: PDRN supports faster healing and cell turnover.
- Anti-Inflammatory Effect: Calms redness and irritation.
- Pigmentation Control: Helps fade PIH (post-inflammatory hyperpigmentation).
- Hydration Boost: Improves overall skin barrier and elasticity.
- Safe & Natural: PDRN is biocompatible and widely used in Korean regenerative dermatology.
Ideal Candidates
Localized PDRN Microneedling in Korea is recommended for:
- Patients with rolling, boxcar, or mixed atrophic acne scars.
- Individuals with sensitive skin or Asian skin types prone to PIH.
- Patients needing targeted therapy rather than full-face microneedling.
- Those seeking regenerative healing with minimal downtime.
- Individuals undergoing multi-session acne scar programs.
Possible Risks & Complications
This treatment is generally safe, but mild and temporary effects may include:
- Redness & Swelling (1–2 days).
- Pinpoint Bleeding or Bruising during microneedling.
- Mild Peeling or Dryness as the skin renews.
- Rare PIH – minimized with Korea’s strict aftercare protocols.
Surgical Techniques Used
- Microneedling Device: Pen or dermastamp with adjustable depth (0.5–2.0 mm depending on scar type).
- Localized Application: Focused stamping or microneedling on acne-scarred zones.
- PDRN Infusion: Regenerative PDRN serums applied into microchannels for deep penetration.
- Combination Therapy: Frequently paired with subcision, RF microneedling, PRP, exosomes, or fractional CO₂ lasers.
Protocol: Typically 3–5 sessions, spaced 4–6 weeks apart.
Recovery & Aftercare
Immediately: Redness, swelling, and mild pinpoint bleeding.
1–3 Days: Redness fades; hydration is key.
1–2 Weeks: Scars begin softening, skin feels firmer.
1–6 Months: Collagen remodeling and PDRN-driven regeneration continue.
Aftercare Tips:
- Avoid makeup for 24 hours post-treatment.
- Use hydrating creams and soothing serums.
- Avoid acids, scrubs, or retinoids for 5–7 days.
- Apply SPF 50+ sunscreen daily to protect healing skin.
Results & Longevity
- After 1 Session: Skin looks plumper and more hydrated.
- After 2–3 Sessions: Noticeable reduction in scar depth and pigmentation.
- After 4–5 Sessions: Long-term collagen remodeling, smoother skin texture, and brighter tone.
- Longevity: Results last 12–18 months, with yearly maintenance recommended.
Treatment Process in Korea
Consultation & Scar Mapping
Dermatologist examines scar severity and selects microneedling depth + PDRN concentration.
Preparation
Topical numbing cream applied; skin sterilized.
Localized PDRN Microneedling Session
- Step 1: Microneedling performed on targeted scarred areas.
- Step 2: PDRN serum infused into the dermis.
- Step 3: Cooling mask or LED red light therapy applied.
Duration: 30–45 minutes.
Why Korea is a Top Destination
- Regenerative Dermatology Expertise: Korea is a global leader in PDRN therapy.
- Precision Protocols: Localized treatment prevents unnecessary trauma to healthy skin.
- Safe for Asian Skin: Minimizes PIH risk compared to aggressive resurfacing.
- Integrated Scar Programs: PDRN often combined with subcision, lasers, or RF for stronger results.
- Affordable Regenerative Care: Lower costs compared to Western clinics offering similar advanced therapies.
Cost Range (Estimated)
- Single Localized PDRN Microneedling Session: USD 250 – 450
- Microneedling + PDRN + LED/Soothing Therapy: USD 350 – 600
- Comprehensive Scar Program (PDRN Microneedling + Subcision/Lasers/Boosters): USD 900 – 1,800 per session
Example Korean Packages:
- Standard Program (3 sessions): USD 700 – 1,200
- Advanced Program (5 sessions with PRP/Exosomes): USD 1,500 – 2,200
- Premium Program (5 sessions with Rejuran/exosomes + fractional laser): USD 2,800 – 3,800
Popular Clinics in Seoul
- Oracle Dermatology: PDRN microneedling with targeted scar correction.
- Banobagi Dermatology: Localized PDRN infusion + subcision and laser therapy.
- Renewme Skin Clinic: PDRN microneedling with exosome boosters.
- View Dermatology: Multi-step scar programs with PDRN + RF microneedling.
- Chaum Anti-Aging Center: Premium PDRN-based scar regeneration programs.



