Treatment Overview
Low-Dose Ovarian Stimulation Therapy in Korea is an advanced, individualized treatment designed for women with Polycystic Ovary Syndrome (PCOS) who are struggling with infertility due to anovulation. PCOS is a complex endocrine disorder that often disrupts ovulatory cycles and reduces fertility. Low-dose ovarian stimulation is a targeted approach that uses carefully calibrated hormone doses to stimulate ovulation while minimizing the risk of ovarian hyperstimulation syndrome (OHSS), a common complication in PCOS treatment.
Korean fertility specialists excel in designing customized stimulation protocols using cutting-edge reproductive medicine technology, real-time follicular monitoring, and AI-assisted hormone mapping. This precision enables patients to respond safely and effectively to ovulation induction while preserving ovarian health. Korea’s integration of medical expertise, technology, and holistic care makes it a global leader in ovarian stimulation therapy.
Purpose & Benefits
The main purpose of low-dose ovarian stimulation therapy is to induce controlled ovulation in women with PCOS, improving their chances of natural conception or assisted reproductive treatment success. Key benefits include:
- Restoration of ovulatory cycles with minimal risk of OHSS
- Better quality of eggs through controlled stimulation
- Increased chances of conception without excessive medication
- Reduced risk of multiple pregnancies compared to high-dose stimulation
- Improved hormonal balance and menstrual regularity
- Shorter and more comfortable treatment cycles with fewer side effects
This therapy is particularly beneficial for PCOS patients who require fertility intervention but wish to avoid the risks of high-dose hormone stimulation.
Ideal Candidates
Low-dose ovarian stimulation is ideal for women with PCOS who:
- Have irregular or absent ovulation
- Have experienced poor response or complications with standard ovarian stimulation
- Are undergoing intrauterine insemination (IUI) or in vitro fertilization (IVF) and require mild stimulation
- Wish to minimize medication dosage for health or comfort reasons
- Are at higher risk of OHSS due to high ovarian reserve
- Seek a tailored, patient-focused approach to fertility treatment
Possible Risks & Complications
Low-dose ovarian stimulation therapy is considered safe when managed by experienced fertility specialists. However, potential risks include:
- Mild bloating, abdominal discomfort, or mood changes
- Ovarian cyst formation
- Mild tenderness or breast sensitivity
- Temporary hormonal changes affecting menstrual cycles
- Rare cases of mild ovarian hyperstimulation, though risks are significantly lower than with high-dose stimulation
Korean fertility centers minimize risks through close monitoring, personalized dosage adjustments, and advanced ultrasound and hormonal tracking during treatment.
Surgical Techniques Used
Low-dose ovarian stimulation is a non-surgical therapy, but Korean clinics may combine it with minimally invasive procedures to enhance results for resistant PCOS cases, including:
- Laparoscopic Ovarian Drilling (LOD): Improves ovarian response in women with high androgen levels.
- Ultrafine Endometrial Preparation: Optimizes the uterine environment for implantation.
- Precision Follicle Monitoring: Uses AI-assisted imaging for accurate dosage and cycle control.
These techniques complement the stimulation process, enhancing success rates and patient safety.
Recovery & Aftercare
Low-dose ovarian stimulation has minimal recovery requirements. Aftercare in Korea includes:
- Frequent ultrasound scans and hormone monitoring during the stimulation cycle
- Lifestyle and nutritional counseling to support fertility and hormone balance
- Guidance on optimal timing for conception or fertility procedures such as IUI or IVF
- Emotional support and stress management strategies
- Optional acupuncture or herbal therapy to support hormonal health
Korean fertility centers ensure that aftercare is integrated into the treatment plan for optimal outcomes.
Results & Longevity
Patients often experience ovulation within 1–2 cycles of starting low-dose stimulation therapy. Success rates vary depending on age, ovarian reserve, and overall health, but Korea’s precision medicine approach significantly increases conception rates. For many PCOS patients, low-dose ovarian stimulation offers sustainable fertility improvement, especially when combined with lifestyle modifications and ongoing hormonal support.
Treatment Process in Korea
The low-dose ovarian stimulation process in Korea typically involves:
- Comprehensive Assessment: Hormonal profiling, ovarian reserve testing, and ultrasound examination.
- Customized Stimulation Protocol: Personalized medication type, dosage, and schedule based on patient profile.
- Cycle Monitoring: Regular ultrasound and blood tests to monitor follicle growth and hormone levels.
- Ovulation Triggering: Administering a trigger injection when follicles reach optimal size.
- Timed Conception or Assisted Reproduction: Coordinating intercourse, IUI, or IVF at peak fertility.
- Follow-Up: Post-cycle hormone evaluation and planning for future cycles or treatment adjustments.
Korea’s emphasis on personalized medicine and advanced cycle monitoring ensures high efficiency and safety in ovarian stimulation therapy.
Cost Range
The cost of low-dose ovarian stimulation therapy in Korea ranges from ₩1,500,000 to ₩4,000,000 KRW (approximately $1,200–$3,000 USD) per cycle. This price generally includes consultation, diagnostic tests, medication, ultrasound monitoring, and follow-up visits. Comprehensive packages that include multiple cycles, additional diagnostics, and integrative therapies may cost between ₩5,000,000 and ₩8,000,000 KRW ($3,800–$6,000 USD).
Popular Clinics
- CHA Fertility Center Seoul Station – Known for customized low-dose ovarian stimulation programs for PCOS.
- Seoul Women’s Hormone & Fertility Clinic – Specializes in personalized stimulation protocols with advanced monitoring.
- Samsung Medical Center (Reproductive Medicine Division) – Offers AI-assisted stimulation management for optimal results.
- Banobagi Women’s Clinic – Combines low-dose ovarian stimulation with holistic PCOS care.
- Ewha Womans University Medical Center – Offers research-based ovarian stimulation programs.
- Mirae Women’s Hospital Seoul – Provides tailored stimulation protocols integrated with comprehensive fertility care.



