Treatment Overview

Mesotherapy is a popular dermatology and aesthetic procedure in Korea that involves microinjections of active ingredients directly into the skin. For post-inflammatory hyperpigmentation (PIH), Korean dermatologists use specialized brightening cocktails containing:

  • Glutathione (antioxidant that reduces melanin production)
  • Vitamin C (skin brightening and collagen booster)
  • Tranexamic Acid (effective for pigmentation suppression)
  • Peptides and Growth Factors (repair and regeneration)
  • Hyaluronic Acid (hydration support)

By delivering these ingredients into the mesoderm (middle skin layer), mesotherapy promotes melanin suppression, skin renewal, and brightening, helping fade PIH while improving hydration and texture.


Purpose & Benefits

  • PIH Reduction: Targets acne-related or trauma-related pigmentation.
  • Direct Delivery: Active ingredients go straight into the skin for higher efficacy than creams.
  • Skin Brightening: Improves dullness and uneven tone.
  • Skin Repair: Supports healing, reduces inflammation, and prevents new pigmentation.
  • Customizable: Korean clinics tailor the cocktail to each patient’s skin needs.
  • Combination-Friendly: Often used alongside lasers (Pico, Nd:YAG, Fraxel) or chemical peels for faster results.

Ideal Candidates

Mesotherapy in Korea is recommended for:

  • Patients with persistent PIH after acne or inflammation.
  • Adults with sensitive skin where lasers might cause irritation.
  • Individuals who prefer injection-based treatment instead of energy devices.
  • Those looking for hydration + brightening + pigment reduction in one treatment.

Possible Risks & Complications

Mesotherapy is generally safe but may cause mild side effects:

  • Redness or Pinpoint Bleeding: Temporary after injections.
  • Swelling or Bruising: Usually resolves in 2–3 days.
  • Itching or Tenderness: Short-term as skin heals.
  • Rare: Allergic reaction if not screened properly.

Korean dermatology clinics minimize risks by using ultra-fine needles, advanced meso-guns, and sterile protocols.


Surgical Techniques Used

  • Microinjections: Delivered manually or with an automated meso-gun for precision.
  • Ingredients: Customized cocktails (Glutathione, Vitamin C, Tranexamic Acid, HA).
  • Protocol: Typically 3–6 sessions, spaced 2–4 weeks apart.
  • Combination Protocols: Often paired with Pico Laser, Nd:YAG toning, or whitening drips.

Recovery & Aftercare

  • Immediately: Mild redness or tiny needle marks.
  • 1–2 Days: Swelling/bruising may occur, especially in sensitive skin.
  • 1 Week: Noticeable hydration and glow; PIH begins to fade gradually.

Aftercare Tips:

  • Avoid makeup for 24 hours post-treatment.
  • Apply SPF 50+ sunscreen daily to prevent new pigmentation.
  • Use gentle, hydrating skincare; avoid acids, scrubs, or retinoids for 3–5 days.
  • Stay hydrated and maintain antioxidant-rich diet to support results.

Results & Longevity

  • After 1–2 Sessions: Skin looks more radiant and hydrated.
  • After 3–4 Sessions: Noticeable fading of PIH and evening of tone.
  • After 5–6 Sessions: Significant reduction in pigmentation, healthier glow.
  • Long-Term: Results last 6–12 months; maintenance every 3–6 months is common in Korea.

Treatment Process in Korea

Korea is globally recognized for its innovative mesotherapy protocols, combining skin science with anti-pigmentation therapy.

  1. Consultation & Skin Analysis
    • Dermatologist assesses PIH type (acne vs trauma), skin sensitivity, and acne activity.
    • Customized cocktail designed for pigmentation + repair.
  2. Preparation
    • Cleansing and topical numbing cream (20–30 minutes).
    • Skin disinfected before injections.
  3. Mesotherapy Session
    • Microinjections delivered across PIH areas or full face.
    • Specialized meso-gun often used for painless, evenly spaced injections.
    • Session lasts 20–40 minutes.
  4. Post-Treatment Care
    • Cooling mask, antioxidant serum, or healing cream applied.
    • Sunscreen applied before discharge.
  5. Follow-Up
    • Recommended course: 3–6 sessions.
    • Often combined with Pico, Nd:YAG toning, or whitening drips for best PIH clearance.

Unique Korean Advantages:

  • Cutting-Edge Cocktails: Customized with Glutathione, Tranexamic Acid, PN, exosomes.
  • Advanced Delivery Systems: Painless meso-guns and microneedling combinations.
  • Integrated Programs: Mesotherapy + lasers + drips for PIH + skin health.
  • Global Reputation: Korea is considered a leader in skin-brightening injection therapy.

Cost Range (Estimated)

  • Single Session (Full Face): USD 150 – 300
  • 3–6 Session Package: USD 500 – 1,200
  • Premium PIH Program (Mesotherapy + Pico/Fraxel/Boosters): USD 1,200 – 2,500

Additional Costs:

  • Consultation: USD 20 – 50
  • Add-ons:
    • Whitening drips (Glutathione, Vitamin C): USD 100 – 200
    • Skin boosters (Rejuran, PN, exosomes): USD 150 – 400
    • Antioxidant masks/serums: USD 50 – 100

Example Korean Packages:

  • Basic Mesotherapy PIH Program (3 sessions): USD 500–700
  • Advanced Brightening Program (Meso + Whitening Drips): USD 900–1,200
  • Premium PIH Program (Meso + Pico/Fraxel + Boosters): USD 1,800–2,500

Popular Clinics in Seoul

  • Oracle Dermatology: Mesotherapy + Pico Laser for acne PIH.
  • Banobagi Dermatology: Brightening mesotherapy with Glutathione & Vitamin C.
  • Renewme Skin Clinic: Meso-cocktails + whitening drips for PIH.
  • View Plastic & Dermatology: Mesotherapy + Fraxel for PIH + scars.
  • Chaum Anti-Aging Center: Premium regenerative mesotherapy with exosomes.

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