Treatment Overview
Micro-Needling with PDRN (Polydeoxyribonucleotide, also known as Salmon DNA therapy) is an advanced skin rejuvenation treatment that combines collagen induction therapy with regenerative injections. In Korea, this therapy is highly popular for dark circles caused by thin skin, fine lines, and poor dermal support.
The procedure involves using a microneedling device or dermapen to create controlled micro-injuries under the eyes, followed by infusion of PDRN. This promotes natural healing, boosts collagen and elastin, and accelerates tissue repair. The result is firmer, brighter, and more youthful under-eyes.
Korean dermatologists often combine microneedling + PDRN with Rejuran i, exosomes, or gentle laser toning for optimal under-eye rejuvenation.
Purpose & Benefits
- Collagen & Elastin Stimulation: Strengthens thin under-eye skin.
- Brightening Effect: PDRN helps repair pigmentation-related dark circles.
- Skin Regeneration: Repairs damaged dermal tissue and reduces fine lines.
- Improved Circulation: Reduces vascular congestion and puffiness.
- Long-Lasting Repair: Enhances skin quality over time.
- Synergy: Works well with PRP, Rejuran i, or Carboxy Therapy.
Ideal Candidates
Micro-Needling with PDRN in Korea for dark circles is recommended for:
- Patients with thin, crepey under-eye skin.
- Individuals with fine lines, wrinkles, or early aging signs.
- Adults with mixed-type dark circles (pigmentation + vascular).
- Those seeking regeneration and long-term improvement rather than temporary fixes.
Comparison with Other Treatments:
- Micro-Needling + PDRN: Best for skin regeneration and dermal strengthening.
- BB Laser / Laser Toning: Best for pigmentation and uneven tone.
- Carboxy Therapy: Best for vascular-related circles.
- Fat Grafting: Best for hollow tear troughs.
- Rejuran i / Exosomes: Best for deeper tissue repair and rejuvenation.
Possible Risks & Complications
The treatment is generally safe but may include temporary side effects:
- Mild Redness or Swelling: Lasts 1–2 days.
- Tiny Pinpoint Marks: Fade within 24–48 hours.
- Bruising (rare): May occur under delicate skin.
- Infection (very rare): Avoided with sterile techniques in Korean clinics.
Treatment Techniques Used
- Micro-Needling Device (Dermapen/Stamp): Creates controlled micro-channels in skin.
- PDRN Infusion: Salmon DNA solution applied or injected into treated area.
- Optional Add-Ons: PRP, exosomes, or Rejuran i for enhanced results.
- Session Protocol: 3–5 sessions, spaced 3–4 weeks apart.
- Combination Therapy: Often combined with gentle laser toning or chemical peels.
Recovery & Aftercare
- Immediately: Redness and slight swelling, similar to a mild sunburn.
- 1–2 Days: Skin calms, feels tighter and smoother.
- 2–4 Weeks: Visible brightening, fewer fine lines, and healthier under-eyes.
Aftercare Tips:
- Apply soothing, hydrating creams or PDRN-based serums.
- Avoid harsh skincare actives (retinol, acids) for 5–7 days.
- Use SPF 50+ daily to protect regenerating skin.
- Avoid makeup or rubbing the under-eye for 24 hours.
Results & Longevity
- Short-Term (1–2 Sessions): Smoother texture, early brightness.
- Medium-Term (3–4 Sessions): Noticeable reduction in dark circles and fine lines.
- Long-Term (6–12 Months): With maintenance every 6–12 months, results continue to improve.
Treatment Process in Korea
- Consultation & Assessment – Doctor evaluates cause of dark circles (pigment, vascular, or structural).
- Preparation – Cleansing, numbing cream applied.
- Micro-Needling Session – Device creates micro-channels in under-eye skin.
- PDRN Application/Injection – Salmon DNA infused for regeneration.
- Optional Add-Ons – PRP, exosomes, or laser toning.
- Post-Care – Cooling mask or peptide serum applied.
- Follow-Up – Sessions scheduled every 3–4 weeks.
Why Korea is a Top Destination
- Clinics specialize in PDRN-based regenerative skin therapies.
- Use of KFDA-approved devices and PDRN solutions ensures safety.
- Dermatologists focus on multi-step dark circle correction.
- More affordable compared to Western clinics, with custom package pricing.
- Seoul is globally recognized for advanced microneedling protocols.
Cost Range (Detailed Breakdown)
Pricing for Micro-Needling with PDRN in Korea for dark circles:
- Single Session: USD 150 – 300
- 3-Session Package: USD 400 – 700
- Micro-Needling + PDRN + PRP/Exosome Combo: USD 300 – 600 per session
- Premium Dark Circle Package (PDRN + Rejuran i + Laser Toning): USD 1,200 – 2,000 (3–5 sessions)
Additional Costs in Korea:
- Consultation: USD 15 – 30
- Add-ons (Exosomes, Rejuran i, PRP): USD 150 – 500
💡 Patients often call Micro-Needling with PDRN the “DNA repair treatment” for dark circles, since it strengthens delicate skin while repairing pigmentation and fine lines.
Popular Clinics in Seoul
- Banobagi Dermatology – Microneedling + PDRN for under-eye repair.
- Oracle Dermatology – PDRN microneedling + exosome combos.
- Renewme Skin Clinic – Regenerative microneedling with PRP or Rejuran i.
- View Plastic & Dermatology – Premium microneedling + laser + PDRN.
- Chaum Anti-Aging Center – Luxury DNA-based eye rejuvenation protocols.
