Treatment Overview
Nucleofill is an advanced polynucleotide (PN)-based skin booster treatment developed to promote deep skin regeneration, collagen stimulation, and elasticity improvement. Unlike hyaluronic acid (HA) boosters that primarily provide hydration, Nucleofill works at the cellular and DNA level to repair damaged skin, improve fibroblast activity, and restore youthful firmness.
In Korea, Nucleofill is widely used in anti-aging programs because it not only improves hydration and fine wrinkles but also strengthens the skin barrier, enhances elasticity, and combats oxidative stress, making it one of the most comprehensive regenerative boosters available today.
Purpose & Benefits
- Collagen & Elastin Stimulation: Activates fibroblasts for long-term firmness.
- Wrinkle Reduction: Improves fine lines and early sagging.
- Elasticity & Density: Strengthens thinning or aging skin.
- Skin Repair: Revitalizes sun-damaged and sensitive skin.
- Anti-Oxidative Protection: Shields skin from stress and inflammation.
- Hydration & Glow: Improves tone and radiance.
- Combination Care: Works well with HA boosters, Rejuran, and exosomes.
Ideal Candidates
Nucleofill in Korea is recommended for:
- Adults in their 20s–70s with early to advanced skin aging.
- Patients with fine wrinkles, sagging, or thinning skin.
- Individuals with acne scars, sun damage, or pigmentation issues.
- Those with sensitive or easily irritated skin.
- Patients seeking regenerative therapy beyond hydration.
Possible Risks & Complications
Nucleofill is very safe with KFDA-approved formulations, but mild effects may occur:
- Redness or Pinpoint Bumps: Common after injections, fade in 24–48 hours.
- Mild Swelling or Bruising: Temporary at injection sites.
- Tightness or Sensitivity: Normal during collagen activation.
- Rare Risks: Allergic reaction or infection (extremely rare in Korea’s top clinics).
Surgical Techniques Used
Though non-surgical, Nucleofill treatments require expert precision protocols:
- Micro-Injections: PN solution injected intradermally.
- Meso-Gun Technology: Ensures even and comfortable distribution.
- Customized Mapping: Adjusted for wrinkles, sagging, or sensitive areas.
- Multi-Session Plan: Typically 3–4 treatments spaced 3–4 weeks apart.
- Combination Therapy: Often paired with HA boosters, Rejuran, or exosomes for maximum results.
Recovery & Aftercare
- Immediately After: Mild redness, bumps, or swelling.
- 1–3 Days: Skin calms; hydration and glow appear.
- 2–4 Weeks: Wrinkles soften; elasticity improves.
- 3–6 Months: Collagen stimulation continues for firmer, healthier skin.
Aftercare Tips:
- Avoid makeup for 24 hours.
- Apply SPF 50+ daily.
- Keep skin moisturized with gentle products.
- Avoid sauna, alcohol, or intense exercise for 1–2 days.
Results & Longevity
- Immediate: Skin feels fresher and more hydrated.
- Short-Term (2–4 Weeks): Wrinkles soften; tone brightens.
- Medium-Term (3–6 Months): Elasticity and density improve.
- Long-Term: Results last 12–18 months, with maintenance sessions once or twice a year.
Treatment Process in Korea
- Consultation & Skin Analysis – Doctor evaluates wrinkles, elasticity, and hydration.
- Preparation – Cleansing; numbing cream applied.
- Injection Session – Nucleofill delivered via micro-needle or meso-gun.
- Post-Care – Cooling masks, serums, or LED therapy applied.
- Follow-Up – Multi-session plan completed for optimal results.
Why Korea is a Top Destination
- Korea is a leader in regenerative skin boosters.
- Access to authentic, KFDA-approved Nucleofill products.
- Dermatologists are skilled in customized combination treatments.
- More affordable than Western medspas with advanced techniques.
- Seoul is globally recognized as the hub of anti-aging and “glass skin” therapies.
Cost Range (Detailed Breakdown)
Pricing for Nucleofill in Korea depends on syringes and treatment programs:
- Single Session (per syringe, 2ml): USD 300 – 500
- Full Face (2–3 syringes): USD 700 – 1,200
- 3-Session Package (recommended): USD 1,500 – 2,800
- Combination Therapy (Nucleofill + Exosomes/Rejuran/HA boosters): USD 700 – 1,500 per session
- Luxury Regeneration Program (Nucleofill + Exosomes/PRP + Threads): USD 3,000 – 5,000
Additional Costs in Korea:
- Consultation: USD 20 – 50
- Numbing & post-care: USD 20 – 40
- Add-ons (PRP, PDO threads, HA boosters): USD 200 – 800
💡 Patients describe Nucleofill as the “DNA repair booster”—restoring elasticity, repairing damage, and protecting skin from aging stressors.
Popular Clinics
- Banobagi Dermatology (Seoul): Leaders in regenerative PN treatments like Nucleofill.
- Oracle Dermatology (Seoul): Offers Nucleofill combined with HA or exosome therapy.
- Renewme Skin Clinic (Seoul): Specialists in scar and elasticity repair using PN boosters.
- View Plastic & Dermatology (Seoul): Combines Nucleofill with PDO threads + Rejuran.
- Chaum Anti-Aging Center (Seoul): Luxury programs with Nucleofill + regenerative add-ons.
