Treatment Overview
PDRN Microneedling is a regenerative dermatology treatment that is highly popular in Korean clinics for improving atrophic acne scars, skin texture, and post-acne pigmentation.
This therapy combines:
- Microneedling – a device with ultra-fine needles creates controlled micro-injuries, stimulating the skin’s natural healing process and boosting collagen and elastin production.
- PDRN (Polydeoxyribonucleotide) – a regenerative compound derived from salmon DNA, infused into the skin through the microneedling channels. PDRN activates fibroblasts, enhances angiogenesis, and accelerates tissue repair, while also reducing inflammation and pigmentation.
In Korea, PDRN microneedling is often paired with subcision, exosomes, PRP, or fractional laser in multi-step acne scar care programs for superior results.
Purpose & Benefits
- Scar Remodeling: Stimulates fibroblasts to rebuild dermal structure and reduce scar depth.
- Accelerated Healing: PDRN supports faster recovery after microneedling.
- Anti-Inflammatory: Calms redness and irritation while promoting skin repair.
- Pigmentation Improvement: Helps fade post-acne dark spots and brighten skin tone.
- Hydration & Barrier Support: Strengthens the skin’s resilience and elasticity.
- Safe & Biocompatible: PDRN is naturally compatible and widely used in regenerative medicine in Korea.
Ideal Candidates
PDRN Microneedling in Korea is recommended for:
- Patients with atrophic acne scars (rolling, shallow boxcar).
- Individuals with sensitive or Asian skin types prone to PIH.
- Patients needing both scar correction and skin tone improvement.
- Those looking for gentle but regenerative treatments with minimal downtime.
- Individuals undergoing multi-session acne scar revision programs.
Possible Risks & Complications
This treatment is generally safe, but mild and temporary effects may occur:
- Redness & Swelling for 1–2 days.
- Pinpoint Bleeding or Bruising during treatment.
- Dryness or Flaking during healing.
- Rare PIH (Post-Inflammatory Hyperpigmentation) – minimized with Korean aftercare standards.
Surgical Techniques Used
- Microneedling Device: Pen or dermastamp with controlled depths (0.5–2.0 mm based on scar type).
- PDRN Infusion: Applied during or after microneedling to penetrate deep into the dermis.
- Combination Protocols: In Korea, commonly paired with subcision, RF microneedling, PRP, exosomes, or fractional CO₂ lasers for advanced scar remodeling.
Protocol: Typically 3–5 sessions, spaced 4–6 weeks apart.
Recovery & Aftercare
Immediately: Redness, swelling, and mild pinpoint bleeding.
1–3 Days: Redness fades; skin feels tighter and hydrated.
1–2 Weeks: Scars appear softened, skin looks brighter.
1–6 Months: Continued collagen remodeling improves scar depth and texture.
Aftercare Tips:
- Avoid makeup for 24 hours post-procedure.
- Use hydrating barrier creams and gentle cleansers.
- Avoid retinoids, acids, and scrubs for 5–7 days.
- Apply SPF 50+ sunscreen daily to prevent pigmentation.
Results & Longevity
- After 1 Session: Skin appears hydrated and slightly firmer.
- After 2–3 Sessions: Noticeable improvement in scar depth, skin tone, and pore size.
- After 4–5 Sessions: Long-term collagen remodeling with smoother, brighter skin.
- Longevity: Results last 12–24 months, with yearly maintenance recommended.
Treatment Process in Korea
Consultation & Skin Analysis
Dermatologist evaluates scar types and selects microneedling depth and PDRN dosage.
Preparation
Topical numbing cream applied; skin sterilized.
PDRN Microneedling Session
- Step 1: Microneedling performed on acne-scarred areas.
- Step 2: PDRN serum infused through microchannels for maximum absorption.
- Step 3: Cooling mask or LED red light applied for calming and healing.
Duration: 40–60 minutes.
Why Korea is a Top Destination
- Leaders in Regenerative Dermatology: Korea pioneered PDRN-based skin therapies.
- Customized Scar Care: Protocols tailored to scar type and skin sensitivity.
- Safe for Asian Skin: Minimized PIH risk compared to harsh laser resurfacing.
- Combination Therapy Culture: Often paired with subcision, RF, or exosomes for synergy.
- Affordable Regenerative Treatments: High-quality programs at lower cost than Western clinics.
Cost Range (Estimated)
- Single PDRN Microneedling Session: USD 250 – 450
- Microneedling + PDRN + LED/Soothing Therapy: USD 350 – 600
- Comprehensive Scar Program (PDRN Microneedling + Subcision/Lasers/Boosters): USD 900 – 1,800 per session
Example Korean Packages:
- Standard Program (3 sessions): USD 700 – 1,200
- Advanced Program (5 sessions with PRP/Exosomes): USD 1,500 – 2,200
- Premium Program (5 sessions with Rejuran/exosomes + fractional CO₂ laser): USD 2,800 – 3,800
Popular Clinics in Seoul
- Oracle Dermatology: PDRN microneedling with scar-targeted therapy.
- Banobagi Dermatology: Acne scar protocols combining PDRN with subcision and lasers.
- Renewme Skin Clinic: PDRN microneedling with PRP/exosome boosters.
- View Dermatology: Multi-step scar care integrating PDRN + RF microneedling.
- Chaum Anti-Aging Center: Premium regenerative scar programs using PDRN.



