Treatment Overview
Plinest is an Italian-developed polynucleotide (PN/PNN) skin booster made from highly purified salmon DNA fragments, and it has become a trusted anti-aging treatment in Korean dermatology clinics. It is especially valued for its ability to stimulate fibroblasts, restore elasticity, and improve dermal density, making it ideal for mild to moderate aging skin.
Unlike hyaluronic acid injectables that focus only on hydration, Plinest repairs skin biologically, activating regeneration, improving texture, and boosting skin firmness.
It belongs to the PN/PNN booster family (Plenhyage XL, Rejuran Healer, Rejuran HB, Juvelook, Aestura PN):
- Plinest: Best for elasticity, skin density, and mid-stage aging.
- Other PN/PNN boosters: Focus on hydration, scars, pigmentation, or advanced laxity.
Purpose & Benefits
- DNA Repair: Restores damaged skin at the cellular level.
- Collagen & Elastin Activation: Improves elasticity and structural integrity.
- Wrinkle Softening: Reduces early to moderate lines and folds.
- Skin Density Strengthening: Thickens fragile or thinning skin.
- Scar Improvement: Helps refine acne scars, stretch marks, and rough texture.
- Hydration & Glow: Boosts natural radiance alongside regeneration.
- Synergy with Other PN/PNN Boosters: Plinest enhances elasticity, while Rejuran or Juvelook focus on repair and scars.
Ideal Candidates
Plinest in Korea is recommended for:
- Adults in their 30s–50s with mild to moderate skin aging.
- Patients with wrinkles, sagging, or early skin laxity.
- Men and women comparing Plinest vs other PN/PNN boosters:
- Plinest: Best for elasticity and structural anti-aging.
- Plenhyage XL: Best for advanced wrinkles and deep laxity.
- Rejuran Healer: Best for overall DNA repair and skin healing.
- Rejuran HB: Best for hydration + repair.
- Juvelook PN: Best for scar correction and fine lines.
- Those seeking preventive anti-aging before advanced aging sets in.
Possible Risks & Complications
Plinest is considered safe in Korean dermatology clinics, but minor temporary side effects may include:
- Redness or Injection Marks: Common, fade within 24–48 hours.
- Mild Swelling or Bruising: Temporary, especially in thinner skin.
- Tightness or Tenderness: Normal for 1–2 days.
- Rare Risks: Uneven absorption or irritation (very rare with expert injection).
Surgical Techniques Used
Though non-surgical, Plinest therapy requires advanced dermatology techniques:
- Micro-Injections: PN/PNN placed into the dermis for elasticity repair.
- Meso-Gun Delivery: Ensures uniform coverage and comfort.
- Targeted Mapping: Focused on wrinkle zones, sagging areas, or scars.
- Layered Protocol: Sometimes combined with Rejuran or PRP for multi-level rejuvenation.
- Multi-Session Plan: Typically 3–4 treatments spaced 3–4 weeks apart, followed by maintenance every 6–9 months.
Recovery & Aftercare
- Immediately: Redness, swelling, or small bumps.
- 1–3 Days: Skin calms; hydration and smoothness improve.
- 2–4 Weeks: Wrinkles soften, elasticity improves, scars fade.
- Maintenance: Every 6–9 months recommended.
Aftercare Tips:
- Avoid makeup for 24 hours.
- Apply SPF 50+ daily.
- Use gentle PN/HA-based serums for hydration.
- Avoid alcohol, saunas, or strenuous workouts for 1–2 days.
Results & Longevity
- Immediate: Skin feels plumper and refreshed.
- Short-Term (2–4 Weeks): Enhanced glow, softer wrinkles, firmer skin.
- Medium-Term (2–3 Months): Collagen remodeling improves density and elasticity.
- Long-Term: Results last 6–9 months, extended with maintenance.
Treatment Process in Korea
- Consultation & Skin Analysis – Doctor evaluates wrinkles, elasticity, and scars.
- Preparation – Cleansing, numbing cream applied.
- Injection Session – Plinest administered via meso-gun or fine needle.
- Optional Add-On: Rejuran, Juvelook, or PRP for enhanced rejuvenation.
- Post-Care: Cooling masks, LED light therapy, soothing serums.
- Follow-Up: 3–4 sessions recommended for optimal elasticity repair.
Why Korea is a Top Destination
- Korea is a global hub for PN/PNN regenerative medicine.
- Clinics use authentic, KFDA-approved Plinest and other PN injectables.
- Dermatologists specialize in elasticity + anti-aging PN protocols.
- Treatments are more affordable than Western medspas, with world-class expertise.
- Seoul is globally recognized for glass skin and anti-aging innovations.
Cost Range (Detailed Breakdown)
Pricing for Plinest in Korea varies depending on the clinic and treatment plan:
- Single Session (full face): USD 300 – 600
- 3-Session Package (recommended): USD 900 – 1,500
- Plinest + PN Combo: USD 700 – 1,500 per session
- Luxury Repair Package (Plinest + Rejuran/Juvelook + PRP/Exosomes): USD 2,000 – 3,800
Additional Costs in Korea:
- Consultation: USD 20 – 50
- Numbing & post-care: USD 20 – 40
- Add-ons (PRP, PDO threads, exosomes): USD 200 – 800
💡 Patients often call Plinest the “elasticity & density booster”, while other PN boosters are known for scars, hydration, or pigmentation. Together, they offer a full-spectrum anti-aging solution.
Popular Clinics
- Banobagi Dermatology (Seoul): Known for Plinest + Rejuran or PRP programs.
- Oracle Dermatology (Seoul): Offers Plinest with PN boosters for anti-aging glow.
- Renewme Skin Clinic (Seoul): Specialized in acne scar + elasticity protocols.
- View Plastic & Dermatology (Seoul): Provides Plinest with exosome and PRP add-ons.
- Chaum Anti-Aging Center (Seoul): Premium PN/PNN elasticity and density care.
