Treatment Overview
Polynucleotide (PN) Boosters are regenerative injectables derived from purified salmon DNA fragments, widely used in Korean dermatology clinics to repair, hydrate, and rejuvenate aging skin. PN molecules stimulate cell renewal, collagen production, and tissue repair, making them highly effective for wrinkles and fine lines caused by dermal thinning and loss of elasticity.
Unlike Botox (which relaxes muscles) or fillers (which add volume), PN boosters target skin quality at the cellular level, repairing damaged dermis and improving density, firmness, and smoothness. Popular PN boosters in Korea include Rejuran Healer, YouthFill PN, and Zenith PN Fusion.
It belongs to the Skin Concerns: Wrinkles & Fine Lines family (Baby Botox, Dermal Fillers, Chanel Injection, Rejuran Healer, Exosome Therapy, Juvelook, Laennec):
- PN Boosters: Best for dermal repair + wrinkle prevention + elasticity.
- Baby Botox: Best for dynamic wrinkles from expressions.
- Fillers: Best for deep static folds.
- Chanel Injection: Best for hydration + fine lines.
- Juvelook / Laennec: Best for biostimulation and regeneration.
Purpose & Benefits
- Wrinkle Reduction: Smooths fine lines around the forehead, eyes, and mouth.
- Collagen Stimulation: Encourages dermal fibroblasts to restore firmness.
- DNA Repair: PN molecules repair damaged tissue and improve dermal health.
- Elasticity Boost: Restores skin resilience against sagging.
- Hydration & Glow: Improves tone, plumpness, and texture.
- Barrier Strengthening: Protects against environmental and oxidative damage.
- Synergy with Other Treatments: Often combined with Botox, exosomes, or HA boosters.
Ideal Candidates
PN Boosters in Korea are recommended for:
- Adults in their 20s–60s with wrinkles, fine lines, or early skin aging.
- Patients with weakened, thinning skin and reduced elasticity.
- Those seeking a regenerative, natural approach to wrinkle repair.
- Men and women comparing treatments:
- PN Boosters: Best for dermal repair + wrinkle prevention.
- Baby Botox: Best for expression wrinkles.
- Fillers: Best for deep wrinkle correction.
- Rejuran / YouthFill PN: Best for DNA-level dermal restoration.
- Exosome Therapy: Best for cellular rejuvenation.
Possible Risks & Complications
PN Boosters are very safe, but mild side effects may occur:
- Redness or Pinpoint Bumps: Common, resolve within 24–48 hours.
- Mild Swelling or Bruising: Temporary at injection sites.
- Tenderness or Tightness: Subsides in 1–2 days.
- Rare Risks: Uneven absorption or irritation (rare with skilled technique).
Surgical Techniques Used
Though non-surgical, PN Boosters require precision for wrinkle correction:
- Micro-Injections: PN molecules injected into the dermis.
- Meso-Gun or Syringe Delivery: Ensures even distribution.
- Targeted Mapping: Wrinkle-prone areas like forehead, crow’s feet, nasolabial folds.
- Combination Therapy: Can be paired with exosomes, HA, or Botox.
- Protocol: 3–4 sessions every 3–4 weeks, with maintenance every 6–9 months.
Recovery & Aftercare
- Immediately: Redness, pinpoint marks, or mild swelling.
- 1–3 Days: Skin calms, early hydration noticeable.
- 2–4 Weeks: Wrinkles begin to smooth; elasticity improves.
- Maintenance: Repeat every 6–9 months for wrinkle prevention.
Aftercare Tips:
- Avoid makeup for 24 hours.
- Apply SPF 50+ daily.
- Use HA- or PN-based hydrating skincare.
- Avoid alcohol, saunas, or strenuous workouts for 1–2 days.
Results & Longevity
- Immediate: Plumper, hydrated skin.
- Short-Term (2–4 Weeks): Fine lines soften, skin feels firmer.
- Medium-Term (2–3 Months): Collagen remodeling strengthens dermis.
- Long-Term: Results last 6–9 months, extendable with maintenance.
Treatment Process in Korea
- Consultation & Skin Analysis – Doctor evaluates wrinkle depth and skin elasticity.
- Preparation – Cleansing and numbing cream applied.
- Injection Session – PN booster infused into dermis via micro-needle or meso-gun.
- Optional Add-Ons – Botox, fillers, exosomes, or HA for stronger results.
- Post-Care – Cooling masks, LED light therapy, or soothing serums.
- Follow-Up – Multi-session protocol ensures optimal wrinkle reduction.
Why Korea is a Top Destination
- Korea is a global leader in PN-based skin regeneration treatments.
- Clinics use authentic, KFDA-approved PN formulations (Rejuran, YouthFill, Zenith PN).
- Dermatologists specialize in wrinkle prevention through regenerative injectables.
- More affordable than Western clinics with advanced precision.
- Seoul is world-renowned for glass skin and anti-aging protocols.
Cost Range (Detailed Breakdown)
Pricing for PN Boosters in Korea varies by brand and package:
- Single Session (full face): USD 300 – 600
- 3–4 Session Package (recommended): USD 900 – 1,600
- PN Booster + Botox/Exosomes/HA: USD 600 – 1,200 per session
- Premium Anti-Aging Package (PN + Exosomes + Botox/Fillers): USD 2,200 – 4,000
Additional Costs in Korea:
- Consultation: USD 20 – 50
- Numbing & post-care: USD 20 – 40
- Add-ons (threads, PRP, exosomes): USD 200 – 800
💡 Patients often call PN Boosters the “DNA wrinkle repair boosters”, since they regenerate skin structure while smoothing fine lines naturally.
Popular Clinics
- Banobagi Dermatology (Seoul): Offers PN boosters + exosomes for wrinkles.
- Oracle Dermatology (Seoul): Combines PN boosters with Botox or HA.
- Renewme Skin Clinic (Seoul): Specialized in PN for fine line prevention.
- View Plastic & Dermatology (Seoul): Provides PN + fillers for wrinkle repair.
- Chaum Anti-Aging Center (Seoul): Premium PN + regenerative wrinkle programs.
