Skin rejuvenation treatments are booming in popularity as more people seek non-surgical ways to restore youthful, radiant skin. Two of the most talked-about options today are Rejuran Healer and Profhilo. Both are injectable treatments designed to improve skin texture, elasticity, and hydration — but they work in different ways and cater to different skin needs.
In this guide, we’ll break down what Rejuran Healer and Profhilo are, how they work, their benefits, and which might be the better option for you.
What Is Rejuran Healer?
Rejuran Healer is a skin booster treatment developed in South Korea that contains polynucleotides (PN) extracted from salmon DNA. These PNs have been shown to promote skin regeneration, reduce inflammation, and improve the skin’s natural barrier.
How Rejuran Works:
- Polynucleotides stimulate the skin’s fibroblasts, enhancing collagen production.
- Reduces skin inflammation and strengthens the skin’s repair mechanisms.
- Helps restore skin elasticity and smooth out fine lines over time.
Benefits of Rejuran Healer:
- Improves overall skin tone and texture
- Repairs damaged skin (especially post-acne)
- Minimizes enlarged pores
- Provides long-term anti-aging effects
- Suitable for sensitive skin types
What Is Profhilo?
Profhilo is a bioremodelling injectable made from 100% pure hyaluronic acid (HA). Unlike traditional dermal fillers, it doesn’t add volume but spreads evenly across the skin to deeply hydrate and stimulate collagen and elastin.
How Profhilo Works:
- Contains one of the highest concentrations of HA on the market (64mg/2ml).
- Is injected at five Bio Aesthetic Points (BAP) on each side of the face.
- Spreads beneath the skin, rehydrating and tightening from within.
- Stimulates the production of collagen and elastin for improved firmness.
Benefits of Profhilo:
- Deeply hydrates and plumps the skin
- Lifts and tightens sagging skin
- Smoothens fine lines and wrinkles
- Improves skin luminosity
- Quick and minimally invasive procedure
Rejuran Healer vs. Profhilo: Key Differences
| Feature | Rejuran Healer | Profhilo |
|---|---|---|
| Main Ingredient | Polynucleotides (Salmon DNA) | Pure Hyaluronic Acid |
| Primary Function | Skin healing & regeneration | Deep hydration & remodeling |
| Injection Method | Multiple microinjections | 5-point BAP injection technique |
| Onset of Results | Gradual, over 2–4 weeks | Quick, within 1–2 weeks |
| Best For | Acne-scarred, damaged, or aging skin | Dry, sagging, or dull skin |
| Treatment Frequency | 3–4 sessions every 3–4 weeks | 2 sessions spaced 1 month apart |
| Longevity | Up to 6–12 months | Up to 6 month |
Which Treatment Is Right for You?
Choose Rejuran Healer if:
- You have acne scars, sensitive, or inflamed skin.
- You’re looking for long-term regenerative effects.
- Your main concern is skin repair and texture improvement.
Choose Profhilo if:
- Your skin is dehydrated, dull, or beginning to sag.
- You want quick hydration and visible plumping.
- Your priority is restoring elasticity and glow.
Can You Combine Rejuran and Profhilo?
Yes, many patients combine both treatments for synergistic benefits. For example, Profhilo can boost hydration and elasticity, while Rejuran focuses on healing and improving skin texture. However, the combination should always be administered by a trained aesthetic practitioner based on your skin’s specific needs.
Conclusion
Both Rejuran Healer and Profhilo are powerful tools in the world of anti-aging and skin rejuvenation, but they serve different purposes. Rejuran is like a “repair serum” for your skin, while Profhilo acts more like a “hydration and lift booster.”
Your choice should depend on your skin condition, goals, and the recommendation of your aesthetic doctor. Whether you go with Rejuran, Profhilo, or both, the result is the same: fresher, healthier, and more radiant skin.
