Treatment Overview
A Repeat Prostate Biopsy is performed when an initial biopsy was inconclusive, negative, or insufficient, but clinical suspicion of prostate cancer remains. This procedure ensures accurate diagnosis and detection of clinically significant cancers that might have been missed during the first biopsy.
Korea offers repeat biopsies using advanced techniques such as targeted lesion biopsy, MRI/ultrasound fusion biopsy, systematic biopsy, and transperineal approaches, ensuring precise sampling and minimal complications. Korean hospitals provide international patients with modern imaging, highly trained urologists, and efficient pathology services.
Purpose & Benefits
The purpose of a repeat prostate biopsy is to:
- Detect prostate cancer missed in the initial biopsy
- Identify clinically significant tumors
- Guide treatment planning, including active surveillance, surgery, or radiation
Benefits include:
- Improved detection rates using advanced imaging and targeting
- Precise tissue sampling from suspicious areas
- Reduced unnecessary cores compared to repeated systematic biopsy
- Safe and minimally invasive procedure
- Fast recovery suitable for outpatient care
Ideal Candidates
Repeat prostate biopsy is recommended for men who:
- Had a previous negative or inconclusive biopsy but elevated PSA persists
- Show suspicious lesions on follow-up MRI or imaging
- Have rising PSA levels or abnormal PSA velocity
- Have a family history of prostate cancer or genetic risk
- Require accurate tumor localization for treatment planning
Korean urologists evaluate each patient to determine the best approach for repeat biopsy.
Possible Risks & Complications
While generally safe, risks include:
- Mild discomfort or soreness at the biopsy site
- Blood in urine, stool, or semen for a few days
- Temporary urinary difficulty
- Infection (rare due to Korea’s strict sterile protocols and antibiotic prophylaxis)
- Rare complications like hematoma or urinary retention
Techniques & Technology Used
Korea uses state-of-the-art technology for repeat biopsies:
- MRI/ultrasound fusion biopsy to target previously missed lesions
- Transperineal or transrectal biopsy depending on patient anatomy and infection risk
- Systematic or targeted approaches for comprehensive sampling
- High-resolution ultrasound for real-time guidance
- Automated spring-loaded biopsy needles for consistent tissue collection
- Local anesthesia or sedation for patient comfort
These technologies ensure accuracy and minimize discomfort during repeat procedures.
Treatment Process in Korea
- Consultation & Evaluation – Review of previous biopsy results, PSA levels, and imaging
- Pre-Biopsy Preparation – Blood tests, antibiotics, and anesthesia planning
- Repeat Biopsy Procedure – Tissue cores collected using the most suitable method
- Observation & Recovery – Short monitoring period before discharge
- Pathology Results – Typically available within 3–5 days, with English-language reports for international patients
Medical tourism coordinators assist with scheduling, translation, and follow-up care.
Recovery & After-Care
- Mild soreness or bruising is common
- Blood in urine or semen may persist for a few days
- Drink plenty of fluids to help recovery
- Avoid heavy exercise and sexual activity for 24–48 hours
- Take prescribed antibiotics
- Contact the hospital if fever, severe pain, or urinary difficulties occur
Results & Longevity
Repeat biopsy results provide:
- Confirmation or exclusion of previously undetected prostate cancer
- Gleason score and Grade Group
- Tumor location and extent
These results guide treatment planning and long-term monitoring. They remain relevant unless PSA rises or new symptoms appear.
Why Korea Is a Top Destination
- Highly skilled urologists specializing in repeat and targeted biopsies
- Advanced imaging and fusion-guided biopsy technologies
- Low infection and complication rates
- Fast scheduling and efficient care for international patients
- English-language support and medical tourism services
- Cost-effective compared to Western countries
Cost Range
Typical costs for a repeat prostate biopsy in Korea:
₩1,500,000 – ₩4,500,000 KRW (~$1,100–$3,500 USD)
Costs vary depending on:
- Biopsy method (fusion-guided, targeted, transperineal, systematic)
- MRI involvement
- Hospital type (private vs. university hospital)
- Number of cores collected
Additional fees may include pre-biopsy tests, consultations, and pathology.
Popular Clinics in Korea
- Seoul National University Hospital – Urology Center
- Samsung Medical Center – Fusion & Targeted Biopsy Program
- Asan Medical Center – Urology Department
- Gangnam Severance Hospital – Advanced Prostate Biopsy Unit
- Korea University Anam Hospital – Targeted & Systematic Biopsy
- JK Urology & Men’s Health Clinics – International Patient Services
