Treatment Overview
Salmon DNA Therapy is one of Korea’s pioneering regenerative skin booster treatments, using polynucleotides (PN) extracted from salmon DNA to heal, repair, and rejuvenate the skin. PN molecules are highly biocompatible and work by stimulating fibroblasts, increasing collagen and elastin production, and strengthening the dermal barrier. This therapy is often seen as the foundation for newer PN boosters like Rejuran.
It is often compared with Nucleofill, another advanced PN-based skin booster:
- Salmon DNA: Primarily targets skin healing, barrier repair, and rejuvenation.
- Nucleofill: Provides elasticity improvement, collagen stimulation, and antioxidant protection.
Korean dermatologists frequently recommend combining them—Salmon DNA for deep healing + Nucleofill for elasticity and long-term regeneration.
Purpose & Benefits
- Skin Healing: Repairs damaged or thinning skin.
- Wrinkle Reduction: Softens fine lines and early folds.
- Collagen & Elastin Boost: Strengthens dermis for firmer texture.
- Scar & Pore Refinement: Improves acne scars and enlarged pores.
- Barrier Strengthening: Protects against sensitivity and environmental stress.
- Brightening Effect: Improves dullness and pigmentation.
- Synergy with Nucleofill: Salmon DNA repairs skin; Nucleofill enhances elasticity and antioxidant defense.
Ideal Candidates
Salmon DNA therapy in Korea is recommended for:
- Adults in their 20s–60s with skin damage or early aging.
- Patients with acne scars, pigmentation, or thinning skin.
- Individuals with sensitive, redness-prone, or sun-damaged skin.
- Men and women comparing Salmon DNA vs Nucleofill:
- Salmon DNA: Best for repair and healing.
- Nucleofill: Best for collagen stimulation and elasticity.
- Patients seeking layered PN protocols for comprehensive regeneration.
Possible Risks & Complications
Salmon DNA is safe in Korea’s dermatology clinics, but mild side effects may occur:
- Redness or Small Bumps: Common post-injection, fade in 24–48 hours.
- Mild Swelling or Bruising: Temporary, especially in delicate areas.
- Tightness or Sensitivity: Normal as skin begins healing.
- Rare Risks: Infection or nodules (extremely rare).
Surgical Techniques Used
Though non-surgical, Salmon DNA therapy requires expert injection techniques:
- Micro-Injections: PN solution delivered intradermally.
- Meso-Gun Technology: Ensures precise, even, and comfortable delivery.
- Customized Mapping: Adjusted for wrinkles, scars, or pigmentation.
- Combination Care: Frequently paired with Nucleofill, Rejuran, or exosomes.
- Multi-Session Plan: Typically 3–4 sessions spaced 3–4 weeks apart.
Recovery & Aftercare
- Immediately After: Mild redness, swelling, or pinpoint bumps.
- 1–3 Days: Skin calms; hydration and glow become visible.
- 2–4 Weeks: Wrinkles soften; scars and pigmentation improve.
- 3–6 Months: Collagen remodeling strengthens skin structure.
Aftercare Tips:
- Avoid makeup for 24 hours.
- Apply SPF 50+ daily.
- Use gentle, hydrating skincare.
- Avoid sauna, alcohol, or heavy workouts for 1–2 days.
Results & Longevity
- Immediate: Skin feels smoother and fresher.
- Short-Term (2–4 Weeks): Wrinkles soften; scars and pigmentation improve.
- Medium-Term (3–6 Months): Elasticity and density increase.
- Long-Term: Results last 12–18 months, extended with Nucleofill protocols.
Treatment Process in Korea
- Consultation & Skin Analysis – Doctor examines wrinkles, scars, and sensitivity.
- Preparation – Cleansing; numbing cream applied.
- Injection Session – PN injected via micro-needle or meso-gun.
- Nucleofill Add-On (Optional): PN booster administered for elasticity and antioxidant repair.
- Post-Care – Cooling masks, LED therapy, or regenerative serums.
- Follow-Up – Multi-session plan scheduled for optimal results.
Why Korea is a Top Destination
- Korea is the origin of PN-based boosters like Salmon DNA and Rejuran.
- Access to authentic, KFDA-approved formulations.
- Dermatologists specialize in dual PN protocols (healing + elasticity).
- Treatments are more affordable compared to Western medspas with higher expertise.
- Seoul is recognized as a global hub for regenerative and anti-aging treatments.
Cost Range (Detailed Breakdown)
Pricing for Salmon DNA in Korea depends on syringes and packages:
- Single Session (per syringe, 2ml): USD 250 – 400
- Full Face (2–3 syringes): USD 600 – 1,000
- 3–4 Session Package (recommended): USD 1,200 – 2,500
- Salmon DNA + Nucleofill Combo: USD 700 – 1,500 per session
- Luxury Regeneration Program (Salmon DNA + Nucleofill + PRP/Exosomes): USD 2,500 – 4,000
Additional Costs in Korea:
- Consultation: USD 20 – 50
- Numbing & post-care: USD 20 – 40
- Add-ons (PRP, PDO threads, exosomes): USD 200 – 800
💡 Patients often describe Salmon DNA as the “original healer” and Nucleofill as the “elasticity protector.” Together, they provide comprehensive skin repair and long-lasting anti-aging.
Popular Clinics
- Banobagi Dermatology (Seoul): Experts in PN-based therapy combinations.
- Oracle Dermatology (Seoul): Offers Salmon DNA for repair + Nucleofill for elasticity.
- Renewme Skin Clinic (Seoul): Specialists in acne scar care with PN boosters.
- View Plastic & Dermatology (Seoul): Combines Salmon DNA with PDO threads + Nucleofill.
- Chaum Anti-Aging Center (Seoul): Luxury regenerative PN programs.
