Treatment Overview
Spironolactone is an oral anti-androgen medication widely prescribed in Korean dermatology clinics for women with hormonal acne. Originally developed as a diuretic, spironolactone works by blocking androgen receptors and reducing androgen activity, which directly decreases sebaceous gland oil production.
Hormonal acne often appears as deep, painful pimples on the jawline, chin, and lower cheeks, typically flaring before menstruation or in women with PCOS (polycystic ovary syndrome). In Korea, dermatologists use low-dose, carefully monitored spironolactone therapy, often alongside topical treatments, acne facials, chemical peels, or LED light therapy for comprehensive acne management.
Purpose & Benefits
- Sebum Regulation: Reduces oil production by blocking androgen stimulation.
- Hormonal Acne Control: Effective for cyclical acne linked to menstruation or PCOS.
- Reduced Breakouts: Decreases frequency and severity of flare-ups.
- Scar Prevention: Fewer severe cysts means lower risk of long-term scarring.
- Non-Isotretinoin Option: Suitable for patients who want an alternative to Accutane.
- Skin Clarity: Improves texture, tone, and acne-related redness over time.
Ideal Candidates
Spironolactone Therapy in Korea is recommended for:
- Women with persistent hormonal acne on the lower face.
- Patients with PCOS-related acne or androgen-driven breakouts.
- Those whose acne worsens before menstruation.
- Individuals who did not respond well to antibiotics, peels, or topical treatments.
- Patients seeking a long-term acne management plan without aggressive treatments.
Possible Risks & Complications
Spironolactone is safe when monitored, but potential side effects may include:
- Menstrual Irregularities (spotting, changes in cycle).
- Breast Tenderness or Mood Changes.
- Increased Urination (as it’s also a diuretic).
- Mild Headaches or Dizziness.
- Contraindications: Not suitable for pregnancy, kidney disease, or certain cardiovascular conditions.
Korean dermatologists prescribe low, tailored doses (typically 25–100 mg/day) to minimize side effects.
Surgical Techniques Used
This is not a surgical treatment but a medically supervised oral therapy. Korean dermatologists typically use:
- Low-Dose Daily Therapy: Starting at 25–50 mg/day, adjusted as needed.
- Combination Protocols: Paired with topical retinoids, salicylic acid peels, or LED light for faster results.
- Ongoing Monitoring: Regular check-ups to assess side effects and progress.
Protocol: Treatment is usually continued for 3–6 months before full results are seen, with long-term maintenance as needed.
Recovery & Aftercare
1–2 Weeks: Oil production may begin to decrease.
1–2 Months: Acne flare-ups lessen in severity.
3–6 Months: Significant improvement in hormonal acne and overall skin clarity.
Aftercare Tips:
- Take medication at the same time daily.
- Attend follow-up visits for monitoring.
- Maintain a consistent skincare routine with gentle cleansers and moisturizers.
- Use SPF 50+ sunscreen daily to protect healing skin.
- Avoid high-potassium supplements unless cleared by a doctor.
Results & Longevity
- After 1 Month: Reduced oiliness and fewer new breakouts.
- After 3 Months: Noticeable improvement in hormonal acne flare-ups.
- After 6 Months: Long-term stability, clearer skin, and improved texture.
Many patients remain clear with continued low-dose spironolactone, sometimes combined with maintenance peels or LED therapy in Korean clinics.
Treatment Process in Korea
Consultation & Hormonal Evaluation
Dermatologist reviews acne history, menstrual cycle, and hormonal triggers. Blood tests may be recommended before starting therapy.
Prescription & Custom Plan
Spironolactone prescribed in low, carefully adjusted doses. Often combined with topical treatments, acne facials, or drips.
Follow-Up & Monitoring
Regular follow-ups every 4–8 weeks ensure safety and effectiveness.
Why Korea is a Top Destination
- Low-Dose Expertise: Korean dermatologists specialize in safe micro-dosing protocols.
- Combination Care: Oral therapy integrated with advanced treatments like LED, Aqua Peel, and chemical peels.
- Scar-Free Focus: Early acne control to prevent scarring, a top priority in Korean clinics.
- Safe for Asian Skin: Tailored regimens minimize risk of PIH (post-inflammatory hyperpigmentation).
- Affordable & Comprehensive Packages: High-quality care at competitive pricing compared to Western clinics.
Cost Range (Estimated)
- Initial Consultation + Prescription: USD 30 – 70
- Monthly Medication: USD 20 – 40
- Combination Care (Oral + Peel/LED): USD 100 – 200 per month
Example Korean Packages:
- Standard Program (3 months): USD 200 – 350
- Acne Care Program (3–6 months with peels/LED): USD 500 – 900
- Premium Program (6 months with supplements, drips, and regenerative boosters): USD 1,000 – 1,800
Popular Clinics in Seoul
- Oracle Dermatology: Hormonal acne care with spironolactone + acne facials.
- Banobagi Dermatology: PCOS-related acne programs with spironolactone therapy.
- Renewme Skin Clinic: Combination care with oral spironolactone and chemical peels.
- View Dermatology: Multi-step hormonal acne treatment including oral therapy.
- Chaum Anti-Aging Center: Premium hormonal acne management with spironolactone + regenerative add-ons.



