Treatment Overview
Stem-Cell Secretome Scalp Injection in Korea is an advanced regenerative hair therapy designed to stimulate hair follicles, improve scalp health, and promote hair regrowth using bioactive molecules secreted by stem cells. Unlike direct stem-cell transplantation, secretome therapy uses the cell-free proteins, growth factors, cytokines, and extracellular vesicles released by mesenchymal stem cells (MSCs).
Korean clinics have pioneered the clinical application of secretome therapy for hair loss, combining it with microneedling, PRP, or peptide therapies to enhance penetration and follicle stimulation. This minimally invasive, biologically advanced treatment is suitable for both male and female pattern hair loss.
Purpose & Benefits
Stem-cell secretome therapy provides multiple regenerative effects:
- Stimulates dormant hair follicles and reactivates growth.
- Strengthens hair shafts and increases follicle density.
- Reduces scalp inflammation, creating a healthier environment for hair growth.
- Enhances vascular supply to follicles.
- Minimally invasive with little to no downtime.
- Can be combined with PRP, microneedling, or peptide injections for superior results.
- Suitable for early-to-moderate thinning hair, making it a preferred option for non-surgical hair restoration.
The therapy is considered safer than cell-based treatments since it eliminates the risk associated with live stem-cell injections.
Ideal Candidates
Stem-Cell Secretome Scalp Injection is recommended for:
- Individuals with androgenic alopecia (male or female pattern baldness).
- Patients with diffuse thinning or miniaturized hair follicles.
- Individuals experiencing stress-related hair shedding (telogen effluvium).
- Post-hair transplant patients looking to enhance graft survival and density.
- Patients who want a non-surgical, biologic hair restoration option.
- Individuals with sensitive scalps who cannot tolerate aggressive injections.
It is less suitable for patients with advanced baldness or fully inactive follicles.
Possible Risks & Complications
Stem-cell secretome injections are generally very safe. Minor temporary effects may include:
- Redness or swelling at injection sites.
- Mild scalp tenderness or itching for 1–2 days.
- Temporary flushing or warmth after treatment.
- Rare sensitivity reactions to the secretome formulation.
Serious adverse effects are extremely uncommon when performed in certified Korean clinics.
Techniques & Technology Used
Korean clinics utilize advanced delivery systems for maximum secretome absorption:
- High-quality MSC secretome prepared under GMP-certified lab standards.
- Automated microneedling devices (0.5–1.5 mm) for deeper penetration of growth factors.
- Direct microinjections into targeted thinning areas.
- Combination therapies including PRP, exosomes, or peptides to enhance outcomes.
- Digital scalp mapping and trichoscopy to assess follicle density and monitor progress.
- Cryopreserved or freshly prepared secretome to ensure bioactivity of proteins and vesicles.
This advanced methodology allows Korean clinics to deliver predictable, safe, and effective results.
Treatment Process in Korea
- Initial Consultation & Scalp Analysis
Dermatologists evaluate hair density, scalp condition, and follicle activity using imaging and trichoscopy. - Customized Secretome Selection
The secretome formula is personalized based on hair loss type, scalp condition, and patient goals. - Scalp Preparation
The scalp is disinfected, and topical numbing may be applied for patient comfort. - Secretome Delivery
- Microinjections or microneedling-assisted delivery into thinning areas.
- Session duration is approximately 30–45 minutes.
- Optional Add-On Treatments
LLLT, PRP, or peptide therapy may be applied to enhance follicle regeneration. - Follow-Up Plan
Typically, 4–6 sessions spaced 2–4 weeks apart are recommended depending on severity.
Recovery & After-Care
- Avoid washing the scalp for 12–24 hours.
- Refrain from saunas, swimming, or heavy sweating for 24 hours.
- Use gentle shampoo and avoid chemical hair treatments for at least 48 hours.
- Do not scratch or massage treated areas for 24 hours.
- Attend all follow-up appointments for optimal monitoring and adjustment.
Most patients can resume normal daily activities immediately after treatment.
Results & Longevity
- Early improvement: Reduced shedding and slight hair thickness improvement in 4–6 weeks.
- Noticeable growth: Hair density and scalp health improve within 2–3 months.
- Maximum results: Typically achieved in 4–6 months with regular sessions.
- Longevity: 6–12 months per treatment cycle; booster sessions extend benefits.
Combination therapy with PRP or microneedling can further enhance and prolong results.
Why Korea Is a Top Destination
- Korea is a global leader in regenerative hair medicine and secretome therapy.
- Access to GMP-certified MSC secretome production facilities.
- Highly trained dermatologists specializing in biologic hair therapies.
- Advanced diagnostic tools for precision scalp and follicle assessment.
- Expertise in combination therapy (secretome + PRP, exosomes, microneedling).
- Cost-effective compared to similar regenerative treatments in Western countries.
- Streamlined medical tourism support for international patients, including translation and post-treatment care.
Korea’s clinical expertise and technological innovation make it an ideal destination for advanced hair regeneration therapies.
Cost Range
- Single session: ₩200,000 – ₩500,000 (USD $150–$380)
- Package (4–6 sessions): ₩800,000 – ₩2,000,000 (USD $610–$1,500)
- Combination with PRP or peptides: ₩1,500,000 – ₩3,500,000 (USD $1,150–$2,700)
Pricing depends on clinic reputation, secretome quality, and additional therapies used.
Popular Clinics in Korea
- Mojelim Hair Transplant & Regeneration Clinic
- Moaman Hair Clinic (Seoul)
- Oracle Dermatology Korea
- Wonjin Dermatology Center
- Gowoonseang Dermatology Network
- Dream Hairline Clinic (Gangnam)
These clinics specialize in MSC secretome therapies and personalized hair regeneration treatment plans.
