Treatment Overview
A Targeted Lesion Biopsy is a precise diagnostic procedure used to detect prostate cancer by specifically sampling suspicious lesions identified on imaging studies such as multi-parametric MRI (mpMRI). Unlike systematic or random biopsies, this technique focuses only on areas with high suspicion, improving accuracy and reducing unnecessary tissue sampling.
Korea is recognized for its advanced diagnostic capabilities, offering high-resolution MRI, MRI–ultrasound fusion technology, and experienced urologists who specialize in precision-guided biopsies. Hospitals in Seoul, Busan, and other major cities provide state-of-the-art facilities and international patient services, making Korea an attractive destination for medical tourists seeking accurate prostate cancer diagnosis.
Purpose & Benefits
The main purpose of a Targeted Lesion Biopsy is to detect clinically significant prostate cancers while minimizing the number of biopsy cores taken. Benefits include:
- Higher detection rate for aggressive or clinically significant tumors
- Reduced discomfort compared to multiple-core systematic biopsies
- Precise localization for treatment planning, including focal therapies
- Reduced risk of overdiagnosis of insignificant lesions
- Shorter procedure time due to fewer cores
- Enhanced patient safety with lower infection risk, especially with transperineal approaches
Ideal Candidates
Targeted Lesion Biopsy is recommended for:
- Patients with suspicious MRI lesions (PI-RADS 3–5)
- Individuals with elevated PSA levels or abnormal PSA velocity
- Men with previous negative systematic biopsies
- Patients planning for focal therapy, robotic surgery, or radiation therapy
- Individuals with a family history of prostate cancer or genetic predisposition
Korean hospitals provide comprehensive evaluation to determine which patients will benefit most from targeted lesion biopsy.
Possible Risks & Complications
Although highly safe, potential risks include:
- Mild pain or discomfort at the biopsy site
- Blood in urine, semen, or stool for a few days
- Temporary urinary difficulty
- Infection (rare due to strict sterilization and antibiotic protocols in Korea)
- Rare cases of urinary retention or hematoma
Korean urology centers minimize complications using sterile techniques, prophylactic antibiotics, and advanced imaging guidance.
Techniques & Technology Used
Korean hospitals utilize state-of-the-art technology for targeted lesion biopsy:
- Multi-parametric MRI (3T MRI) to identify suspicious lesions
- MRI–ultrasound fusion guidance for real-time targeting
- Transrectal or transperineal biopsy approaches based on patient anatomy and risk factors
- High-precision biopsy needles and automated systems
- 3D prostate mapping software for accurate lesion localization
- Local anesthesia or sedation to ensure patient comfort
These technologies allow urologists to accurately target specific lesions with minimal cores, reducing procedural time and patient discomfort.
Treatment Process in Korea
The process is smooth and patient-friendly for international patients:
- Consultation & Evaluation – Review of PSA, MRI, and medical history
- Pre-Biopsy Preparation – Blood tests, antibiotics, anesthesia planning
- Imaging & Fusion Setup – MRI images integrated with real-time ultrasound
- Targeted Biopsy Procedure – Needle guided precisely to suspicious lesions
- Observation & Recovery – Short monitoring period before discharge
- Pathology Report – Usually ready within 1–3 days
Korean hospitals offer international patient coordinators to help with scheduling, translation, and follow-up.
Recovery & After-Care
- Mild soreness or bruising at the biopsy site is normal
- Temporary blood in urine or semen may occur for a few days
- Drink plenty of fluids to aid recovery
- Avoid strenuous exercise and sexual activity for 24–48 hours
- Take prescribed antibiotics as instructed
- Contact the hospital if fever, severe pain, or urinary difficulties occur
Korean clinics provide thorough post-procedure guidance and remote consultation for international patients.
Results & Longevity
Targeted lesion biopsy provides detailed information about:
- Gleason score and Grade Group
- Tumor location and size
- Percentage of cancer involvement per core
These results are critical for planning treatment, including focal therapies, robotic surgery, or radiation. The results are highly reliable and remain relevant for long-term prostate management unless PSA rises or new symptoms appear.
Why Korea Is a Top Destination
- Highly skilled urologists specializing in precision biopsies
- Cutting-edge MRI and fusion biopsy technology
- Extremely low infection and complication rates
- Fast scheduling and efficient care
- English-language support for international patients
- Cost-effective compared to Western countries
Korea combines advanced technology, clinical expertise, and patient-centered care, making it an ideal destination for medical tourists.
Cost Range
Typical costs for targeted lesion biopsy in Korea:
₩1,800,000 – ₩3,800,000 KRW (~$1,350–$2,900 USD)
Factors affecting cost:
- MRI imaging quality (3T vs 1.5T)
- Fusion guidance technology
- Hospital type (private vs university hospital)
- Number of biopsy cores collected
Additional fees may include blood tests, pathology, and consultation.
Popular Clinics in Korea
- Seoul National University Hospital – Precision Urology Center
- Samsung Medical Center – MRI Fusion Biopsy Unit
- Asan Medical Center – Urology Oncology Division
- Gangnam Severance Hospital – Targeted Prostate Biopsy Program
- Korea University Anam Hospital – Advanced Imaging & Biopsy
- JK Urology & Men’s Health Clinics – International Patient Services
