Treatment Overview
Tranexamic Acid Therapy is a widely used treatment in Korean dermatology for post-inflammatory hyperpigmentation (PIH), melasma, and stubborn pigmentation disorders.
Originally developed as an anti-fibrinolytic medication to control bleeding, TXA was later found to inhibit melanocyte activity and reduce pigmentation. In Korea, dermatologists use TXA in multiple forms: oral tablets, topical creams/serums, intradermal injections (mesotherapy), and IV drips.
TXA is often used as a standalone therapy or in combination with lasers (Nd:YAG, Pico, Sylfirm X) and PRP/skin boosters for enhanced results and prevention of PIH recurrence.
Purpose & Benefits
- PIH Clearance: Inhibits melanin overproduction after acne or skin inflammation.
- Melasma-Friendly: Effective for mixed pigmentation resistant to lasers.
- Prevents Recurrence: Reduces the chance of pigmentation returning after laser therapy.
- Safe for Asian Skin: Gentle action without risk of rebound pigmentation.
- Multi-Delivery Options: Oral, injection, or topical use depending on severity.
Ideal Candidates
Tranexamic Acid therapy in Korea is recommended for:
- Patients with PIH from acne, injury, or inflammation.
- Individuals with melasma or chronic pigment issues.
- Adults who want low-risk treatment for sensitive or Asian skin types.
- Patients seeking combination therapy to enhance laser/PRP results.
Possible Risks & Complications
TXA is generally safe and widely studied in dermatology. However, possible risks vary by delivery method:
- Oral TXA: Rare risk of blood clotting in predisposed patients (screening required).
- Injections/IV: Mild bruising or swelling at injection sites.
- Topical TXA: Minimal irritation or redness in sensitive skin.
Korean dermatologists typically use low-dose regimens and screen patients for clotting disorders to ensure safety.
Techniques Used
- Oral TXA: Low-dose tablets (commonly 250 mg, 1–2 times daily).
- Intradermal Injections (Mesotherapy): Small amounts injected into PIH or melasma patches.
- Topical TXA Creams/Serums: Applied directly to dark spots for long-term maintenance.
- IV TXA Drips: Combined with whitening cocktails (Vitamin C, Glutathione) in premium programs.
Protocol: Typically 8–12 weeks of treatment, with results improving gradually. Maintenance often needed for chronic pigmentation.
Recovery & Aftercare
Immediately: No downtime for oral/topical; mild swelling possible with injections.
1–2 Weeks: Subtle skin brightening, gradual fading of dark spots.
1–3 Months: Significant PIH and melasma reduction.
Aftercare Tips:
- Strict use of SPF 50+ sunscreen daily.
- Continue hydrating skincare and antioxidants.
- Avoid excessive sun exposure and skin trauma.
- Combine with gentle lasers or PRP for optimal results.
Results & Longevity
- After 2–4 Weeks: Brighter tone, reduced dark patches.
- After 8–12 Weeks: Noticeable clearance of PIH and melasma.
- Long-Term: Results last with ongoing maintenance (oral/topical TXA, periodic boosters).
- Combination Therapy: Works best alongside Nd:YAG/Pico for stubborn PIH.
Treatment Process in Korea
Consultation & Screening
- Dermatologist reviews pigmentation type and medical history.
- Screening for clotting risk before oral or IV TXA.
Preparation
- Bloodwork if oral/IV TXA is prescribed.
- Skin cleansing before mesotherapy injections.
TXA Session
- Oral tablets or topical prescribed for home use.
- Intradermal injections delivered into PIH or melasma spots.
- IV whitening drip (TXA + antioxidants) for systemic brightening.
- Duration: 15–30 minutes per session.
Post-Treatment Care
- Cooling mask or brightening serum (if injections used).
- Emphasis on sun protection and daily skincare.
Follow-Up
- Typically 8–12 weeks of therapy.
- Maintenance may continue with topical TXA or periodic injections.
Unique Korean Advantages
- Multi-Modal Approach: Oral + topical + injection/IV for maximum efficacy.
- Combination Programs: Often paired with lasers, PRP, or skin boosters.
- Tailored Protocols: Customized for melasma/PIH-prone Asian skin.
- Global Reputation: Korea is recognized as a leader in pigmentation protocols.
Cost Range (Estimated)
- Oral TXA (per month): USD 50 – 150
- Topical TXA Serums/Creams: USD 80 – 200
- Injection/Mesotherapy Session: USD 150 – 300
- IV Whitening Drip (TXA + Vitamins): USD 200 – 400
Example Korean Packages:
- Basic TXA PIH Program (Oral + Topical, 8 weeks): USD 300–500
- TXA Mesotherapy (3 sessions): USD 500–800
- Premium Whitening Program (TXA IV + Lasers/Boosters): USD 1,500–2,500
Popular Clinics in Seoul
- Oracle Dermatology: TXA mesotherapy + Nd:YAG for PIH.
- Banobagi Dermatology: TXA oral + Pico combo for melasma.
- Renewme Skin Clinic: TXA whitening drips + PRP.
- View Plastic & Dermatology: TXA + Fraxel for pigment + texture.
- Chaum Anti-Aging Center: Premium TXA IV + regenerative boosters.
