Treatment Overview
Y-chromosome microdeletion testing is a specialized genetic test that identifies deletions in the Y chromosome, which can cause severe male infertility. These deletions may impact sperm production, leading to low sperm count (oligospermia) or absence of sperm (azoospermia). Clinics in Korea provide advanced molecular testing to guide fertility evaluation and personalized treatment strategies.
Purpose & Benefits
The main purposes of Y-chromosome microdeletion testing are:
- Detecting deletions in the Y chromosome affecting sperm production
- Identifying genetic causes of male infertility
- Guiding assisted reproductive treatment strategies such as IVF or ICSI
Benefits include:
- Precise identification of genetic factors affecting fertility
- Improved decision-making for fertility treatment planning
- Avoiding unnecessary treatments when genetic causes are identified
- Early counseling on hereditary risks for potential offspring
Ideal Candidates
Y-chromosome microdeletion testing is recommended for:
- Men with severe oligospermia (very low sperm count)
- Individuals with azoospermia (absence of sperm)
- Men with abnormal semen analysis results
- Patients with a family history of genetic disorders affecting fertility
- Couples planning assisted reproductive techniques such as IVF or ICSI
Possible Risks & Complications
Y-chromosome microdeletion testing is safe and minimally invasive. Possible considerations include:
- Minor discomfort or bruising at the blood collection site
- Psychological stress related to genetic results
- Rare concerns regarding confidentiality of genetic information
There are no serious physical risks associated with the procedure.
Techniques & Technology Used
Korean clinics use advanced genetic and molecular techniques for Y-chromosome microdeletion testing:
- Blood or saliva sample collection – Standard method for DNA extraction
- PCR (Polymerase Chain Reaction) analysis – Detects specific deletions in the Y chromosome
- Microarray analysis or sequencing – Confirms and maps genetic deletions
- Integration with fertility testing – Combined with semen analysis, sperm DNA testing, and hormone evaluation
These methods ensure accurate identification of deletions and provide actionable insights for treatment.
Treatment Process in Korea
The testing process typically includes:
- Consultation: Review of medical and reproductive history, previous semen analysis results
- Sample Collection: Blood or saliva collected at the clinic or hospital
- Laboratory Analysis: Molecular genetic testing to detect Y-chromosome deletions
- Results Interpretation: Detailed report with professional guidance and recommendations
- Follow-Up: Counseling on fertility treatment options or assisted reproduction strategies
Recovery & After-Care
No recovery is required. After-care includes:
- Reviewing results with a fertility specialist
- Following recommendations for assisted reproductive treatment if required
- Maintaining confidentiality of genetic information
Results & Longevity
Results provide insight into the genetic causes of male infertility:
- Identification of Y-chromosome deletions that affect sperm production
- Guidance for personalized treatment, including IVF or ICSI
- Information on hereditary risks for potential offspring
Results are permanent and useful for long-term fertility planning.
Why Korea Is a Top Destination
Korea is a leading destination for Y-chromosome microdeletion testing due to:
- Advanced genetic laboratories with precise molecular diagnostics
- Experienced reproductive endocrinologists and genetic counselors
- Integration with comprehensive male fertility evaluation and treatment programs
- Confidential, patient-centered, and English-friendly services
- Competitive pricing and internationally accredited clinics
Cost Range
Y-chromosome microdeletion testing in Korea typically costs $500 to $1,500 USD, depending on the complexity of the test and whether it is part of a full fertility evaluation package.
Popular Clinics in Korea
Top clinics for Y-chromosome microdeletion testing include:
- Banobagi Medical Group – Complete genetic and fertility evaluation
- Grand Seoul Hospital – Advanced reproductive genetics and counseling
- JK Plastic Surgery & Medical Clinic – Integrated genetic, hormone, and fertility assessment
- ID Hospital – International patient-friendly male fertility genetic testing
